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The smooth muscle cell in culture.
Physiological Reviews, 1979The current state of knowledge of both vascular and visceral smooth muscle in cell and tissue culture and the variety of preparations used for different experimental purposes are described. Organ culture of smooth muscle tissues is referred to only periodically.
J. Chamley-Campbell +2 more
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Reference Module in Biomedical Sciences, 2021
Vascular smooth muscle cells (SMCs) are very quiescent in the mature vessel and exhibit a remarkable phenotype-dependent diversity in gene expression that may reflect the growth responsiveness of these cells under a variety of normal and pathological ...
S. E. Epstein +5 more
semanticscholar +3 more sources
Vascular smooth muscle cells (SMCs) are very quiescent in the mature vessel and exhibit a remarkable phenotype-dependent diversity in gene expression that may reflect the growth responsiveness of these cells under a variety of normal and pathological ...
S. E. Epstein +5 more
semanticscholar +3 more sources
Cytokeratins in smooth muscle cells and smooth muscle tumours
Histopathology, 1988A keratin positive metastatic leiomyosarcoma in the lung, which resulted in diagnostic error, is reported. The results of additional studies of 17 benign and malignant leiomyogenic tumours with various keratin antibodies are presented and discussed in the light of recent bibliographical data.
F C, Ramaekers +2 more
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Smooth muscle cells and atherosclerosis
Current Opinion in Lipidology, 1995The role of smooth muscle cells in atherogenesis involves cell proliferation and accretion of cholesteryl ester. Smooth muscle cell proliferation, controlled by growth factors produced locally, contributes to progression of atheroma and to restenosis after percutaneous transluminal coronary angioplasty.
O, Stein, Y, Stein
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Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity.
Cellular Signalling, 2018Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike many other mature cell types in the adult body, VSMC do not terminally differentiate but retain a remarkable plasticity.
Agne Frismantiene +3 more
semanticscholar +1 more source
The Vascular Smooth Muscle Cell In Culture
Thrombosis and Haemostasis, 1981When smooth muscle from the aortic media of adult pigs, monkeys and rabbits are dispersed into single cells and seeded into primary culture they are in the contractile phenotype and do not undergo cell division when challenged with 5 or 10% whole blood serum.
Campbell, GR, Chamleycampbell, JH
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Contraction in the smooth muscle cell
Medical Hypotheses, 1999This paper advances the hypothesis that the rearrangement of the actin cytoskeleton that takes place during contraction in the SMC is a mechanical reflection of the spatiotemporal pattern of the cell's polarized stimulus. In that sense the cell is responding more like a motile non-muscle cell than like a skeletal muscle cell.
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2005
Proliferation and migration of smooth muscle cells (SMCs) from the media towards the intima are key events in atherosclerosis and restenosis. During these processes, SMC undergo phenotypic modulations leading to SMC dedifferentiation. The identification and characterization of factors controlling these phenotypic changes are crucial in order to prevent
Bochaton-Piallat, Marie-Luce +1 more
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Proliferation and migration of smooth muscle cells (SMCs) from the media towards the intima are key events in atherosclerosis and restenosis. During these processes, SMC undergo phenotypic modulations leading to SMC dedifferentiation. The identification and characterization of factors controlling these phenotypic changes are crucial in order to prevent
Bochaton-Piallat, Marie-Luce +1 more
openaire +4 more sources
Smooth Muscle Cell and Atherosclerosis
1975There now is general agreement that the principal feature of the lesions of atherosclerosis is the proliferation of smooth muscle cells within the intima of the artery wall [1]. This intimal smooth muscle proliferative response is associated with formation of relatively large amounts of connective tissue matrix constituents, including collagen, elastic
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The Collagenous Exocytoskeleton of Smooth Muscle Cells
Collagen and Related Research, 1981Abstract Using specific antibodies in immunoelectron microscope studies with vascular tissues, type V collagen has been localized in basement membrane structures associated with discrete regions of the smooth muscle cell surface as well as membranous structures adjacent to endothelial cell membranes.
S, Gay +3 more
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