Results 281 to 290 of about 29,268 (294)

Vertebrate Smoothened functions at the primary cilium

Nature, 2005
K. Corbit, P. Aanstad, Veena Singla, Andrew R. Norman, D. Stainier, Jeremy F. Reiter   +5 more
semanticscholar   +1 more source

Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation

Cell Reports, 2017
Matthew W Frank, Charles O ROCK, Stacey K Ogden   +2 more
exaly  

Smoothened Regulation: A Tale of Two Signals

Trends in Pharmacological Sciences, 2016
Suresh Marada, Stacey K Ogden
exaly  

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

ACS Medicinal Chemistry Letters, 2010
Shifeng Pan, Xu Wu, Yongqin Wan
exaly  

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Nature, 2000
J. Taipale, James K. Chen, M. K. Cooper, Baolin Wang, R. K. Mann, Ljiljana Milenkovic, M. Scott, P. Beachy   +7 more
semanticscholar   +1 more source

Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened

Structure, 2019
George Hedger, Heidi Koldsø, Matthieu Chavent   +2 more
exaly  

Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened

ACS Medicinal Chemistry Letters, 2012
Qifang Li, Christopher S Jones
exaly  

N-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonists

Bioorganic and Medicinal Chemistry Letters, 2011
Alberto Bresciani, Claudio Giuliano, Christian Steinkuhler   +2 more
exaly  

Smoothened antagonists for hair inhibition

Bioorganic and Medicinal Chemistry Letters, 2010
Veerabahu Shanmugasundaram, Manju Swaroop, Danielle Dettling   +2 more
exaly  

Patched1–ArhGAP36–PKA–Inversin axis determines the ciliary translocation of Smoothened for Sonic Hedgehog pathway activation

Proceedings of the National Academy of Sciences of the United States of America, 2019
Boyan Zhang, Tenghan Zhuang, Qiaoyu Lin   +2 more
exaly