Results 291 to 300 of about 2,656,785 (305)

Structural Basis of Smoothened Activation in Hedgehog Signaling

Cell, 2018
Sanduo Zheng, Bradley M Wierbowski, Youngchang Kim   +2 more
exaly  

Hedgehog Induces Opposite Changes in Turnover and Subcellular Localization of Patched and Smoothened

Cell, 2000
Lidia Perez
exaly  

G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling

Nature, 2008
Stacey K Ogden, David J Robbins, Dennis Liang Fei   +2 more
exaly  

Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened

Structure, 2019
George Hedger, Heidi Koldsø, Matthieu Chavent   +2 more
exaly  

Structure of the human smoothened receptor in complex with ANTA XV

, 2014
Chong Wang, Huixian Wu, Tama Evron, E. Vardy, G. Han, Xi Ping Huang, S. Hufeisen, T. Mangano, D. Urban, V. Katritch, V. Cherezov, M. Caron, B. Roth, R. Stevens   +13 more
semanticscholar   +1 more source

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Nature, 2000
Jussi Taipale, Randall K Mann, Philip A Beachy   +2 more
exaly  

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling

Cell, 2016
Youngchang Kim, Jing Liu, Adrian Salic
exaly  

Human Smoothened Receptor structure in complex with cyclopamine

, 2014
Chong Wang, U. Weierstall, Daniel James, T. White, Dingjie Wang, Wei Liu, J. Spence, R. Doak, G. Nelson, P. Fromme, R. Fromme, I. Grotjohann, Christopher Kupitz, N. Zatsepin, Haiguang Liu, S. Basu, Daniel Wacker, G. Han, V. Katritch, S. Boutet, M. Messerschmidt, G. Willams, J. Koglin, M. Seibert, M. Klinker, C. Gati, R. Shoeman, A. Barty, H. Chapman, R. Kirian, K. Beyerlein, R. Stevens, Dianfan Li, Syed T. A. Shah, N. Howe, M. Caffrey, V. Cherezov   +36 more
semanticscholar   +1 more source

Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists

Cancer Cell, 2013
James Kim, Jean Tang, Alexandra Borodovsky   +2 more
exaly  

Smoothened Regulation: A Tale of Two Signals

Trends in Pharmacological Sciences, 2016
Suresh Marada, Stacey K Ogden
exaly