Results 61 to 70 of about 889,338 (324)
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
A color representation of two-dimensional discontinuous seismic structures [PDF]
We present a computational procedure to represent with colors two-dimensional piecewise continuous functions. Seismic wave velocities are used as examples.
J. Acosta, J. Frez
doaj
In the course of the COVID-19 pandemic and the implementation of associated non-pharmaceutical containment measures, the need for continuous monitoring of the mental health of populations became apparent.
Stephan Junker +3 more
doaj +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Constructing Wildebeest Density Distributions by Spatio-temporal Smoothing of Ordinal Categorical Data Using GAMs [PDF]
Spatio-temporal smoothing of large ecological datasets describing species distributions can be made challenging by high computational costs and deficiencies in the available data.
Ferguson, Elaine A. +2 more
core
The notion of a formally smooth bimodule is introduced and its basic properties are analyzed. In particular it is proven that a $B$-$A$ bimodule $M$ which is a generator left $B$-module is formally smooth if and only if the $M$-Hochschild dimension of $B$ is at most one. It is also shown that modules $M$ which are generators in the category $ [M]$ of $
ARDIZZONI, Alessandro +2 more
openaire +5 more sources
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
An allometric smoothing function to describe the relation between otolith and somatic growth over the lifespan of walleye pollock (Theragra chalcogramma) [PDF]
We propose a new equation to describe the relation between otolith length (OL) and somatic length (fork length [FL]) of fish for the entire lifespan of the fish.
Ikeda, Hisatoshi +4 more
core +1 more source
Handling Overlapping Asymmetric Data Sets—A Twice Penalized P-Spline Approach
Aims: Overlapping asymmetric data sets are where a large cohort of observations have a small amount of information recorded, and within this group there exists a smaller cohort which have extensive further information available.
Matthew McTeer +3 more
doaj +1 more source
The work of Professor Andrzej Lasota on asymptotic stability and recent progress [PDF]
The paper is devoted to Professor Andrzej Lasota's contribution to the ergodic theory of stochastic operators. We have selected some of his important papers and shown their influence on the evolution of this topic. We emphasize the role A.
Wojciech Bartoszek
doaj

