Results 91 to 100 of about 105,238 (268)
Jabba: hybrid error correction for long sequencing reads [PDF]
, 2016 Background: Third generation sequencing platforms produce longer reads with higher error rates than second generation technologies. While the improved read length can provide useful information for downstream analysis, underlying algorithms are ...
Audenaert, P. +6 more
core +3 more sources
PPARα and NCOR/SMRT corepressor network in liver metabolic regulation
The FASEB Journal, 2020 Peroxisome proliferator‐activated receptor alpha (PPARα, NR1C1) belongs to a large family of ligand‐dependent nuclear receptors (NRs). It is one of the best studied NRs which controls the lipid metabolism (mainly fatty acid oxidation) and inflammation ...
Z. Kang, Rongrong Fan
semanticscholar +1 more source
Pest Management Science, EarlyView.This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses. [PDF]
, 2015 Antiretroviral therapy, antibody and CD8+ T cell-mediated responses targeting human immunodeficiency virus-1 (HIV-1) exert selection pressure on the virus necessitating escape; however, the ability of CD4+ T cells to exert selective pressure remains ...
Allen, S +16 more
core +3 more sources
Phytotherapy Research, EarlyView.Baicalin restores the hypoglycemic effect of metformin by decreasing the serum imidazole propionate. ABSTRACT Gut microbiota dysbiosis is implicated in metformin non‐response. This study aimed to investigate whether baicalin, a microbiota‐modulating flavonoid derived from Radix Scutellariae, could restore metformin sensitivity and explored the ...
Aiting Wang +5 more
wiley +1 more source
The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. [PDF]
PLoS ONE, 2013 Checkpoint kinase 2 (Chk2) is a major regulator of DNA damage response and can induce alternative cellular responses: cell cycle arrest and DNA repair or programmed cell death.
Claudio Scafoglio +4 more
doaj +1 more source
, 2012 Der folgende Text gehört zur kritischen Thanatologie. In allen bekannten Kulturen wurden Normen für den guten und den schlechten Tod von der herrschenden normativen Thanatologien aufgestellt und Kontrollmechanismen installiert. Prämortales und postmortales soziales Sterben ist eine Art der Exklusion der Anderen und wird unterschiedlich bestimmt: als ...
openaire +2 more sources
Electroelution Into a Salt Trap: Reviving an Old‐School Approach to DNA Purification
Small Methods, EarlyView.Electroelution into a salt cushion is a well‐established yet underutilized method of capturing gel‐purified nucleic acids. This Perspective discusses how this traditional method can be reengineered to meet the demands of next‐generation technologies, such as long‐read sequencing.
Ruslan Kalendar +4 more
wiley +1 more source
Draft Genome of Janthinobacterium sp. RA13 Isolated from Lake Washington Sediment. [PDF]
, 2015 Sequencing the genome of Janthinobacterium sp. RA13 from Lake Washington sediment is announced. From the genome content, a versatile life-style is predicted, but not bona fide methylotrophy.
Chistoserdova, Ludmila +3 more
core +1 more source
Insect Science, EarlyView.The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu +6 more
wiley +1 more source