Results 31 to 40 of about 38,322 (233)

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Je li smrt zadnja riječ? [PDF]

, 1977
Prikaz knjige Gerharda Lohfinka, Der Tod ist nicht das letzte Wort (Smrt nije zadnja riječ), Herder, Freiburg ...
Kusić, Ante
core   +1 more source

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.

PLoS ONE, 2019
Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) and the nuclear receptor co-repressor1 (NCoR1) are paralogs and regulate nuclear receptor (NR) function through the recruitment of a multiprotein complex that includes histone ...
Hiroaki Shimizu, Yu Lu, Kristen R Vella, Federico Damilano, Inna Astapova, Izuki Amano, Megan Ritter, Molly R Gallop, Anthony N Rosenzweig, Ronald N Cohen, Anthony N Hollenberg   +10 more
doaj   +1 more source

Pohřbívání na Moravě v 16.–18. století

Archaeologia Historica, 2017
Výsledky studia pohřebního ritu v novověku představují zdroj informací o sociální struktuře tehdejší společnosti, o jejích postojích ke smrti a víře a v neposlední řadě o zvyklostech, které můžeme srovnávat s jevy jiných historických období.
Michaela Králíková
doaj   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Andragogika vsakdanjega življenja – učenje ob doživljanju smrti

AS: Andragoška Spoznanja, 2008
Smrt je rite de passage, s katerim se vsakdo sreča ob umiranju bližnjih, a še vedno razmeroma malo vemo, kako vpliva na posameznika. Besedilo poskuša odpreti razmišljanje o učenju v obdobju žalovanja in dodati drobec k razumevanju učenja kot ...
Nives Ličen, Maja Furlan, Simona Šinko
doaj   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

PacBio sequencing output for each SMRT cell.

, 2019
PacBio sequencing output for each SMRT cell.
Narjol González-Escalona (280578), Eric W. Brown (213283), Marc A. Allard (7067681), Shashi Sharma (282487), Maria Hoffmann (720254)   +4 more
core   +1 more source

Public relations in Singapore: The Love-Hate relationship with social media [PDF]

, 2012
The growth of social media has undoubtedly impacted upon public relations practice even in non-liberal societies. In December 2011, operators of Singapore 19s metro train system, the Singapore Mass Rapid Transit (SMRT) Corporation, suffered a ...
Heng, Edmund Wei-Loong
core