Results 41 to 50 of about 32,958 (246)

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

Kenoza križa u teološkoj misli Hansa Ursa von Balthasara

open access: yesStudia Lexicographica, 2014
Hans Urs von Balthasar prikazuje teologiju križa kao događaj Boga (kenoza), koji se mora shvatiti kao otkrivenje cjelokupnoga Trojstva. Trojstvena drama, koja se ostvaruje u razlikovanju božanskih hipostaza i njihovom unutartrojstvenom predanju snagom ...
Nikola Turkalj
doaj  

Representações Sociais de Gestores da Saúde sobre Competências, Saúde Mental e Trabalho

open access: yesPsicologia, 2023
O objetivo da pesquisa foi analisar as representações sociais dos trabalhadores em cargos de gestão acerca das competências para atuar sobre a saúde mental relacionada ao trabalho (SMRT), e como elas podem contribuir ou dificultar o desenvolvimento ...
Leonardo Alexandrino de Almeida   +3 more
doaj   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

open access: yesAdvanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren   +20 more
wiley   +1 more source

Over-expression of the RD4 region of SMRT inhibits HDAC inhibition-mediated SMRT export.

open access: yes, 2013
A) Upper: Over-expression of RD4 inhibits TSA-mediated nuclear export of SMRT. Neurons were transfected with GFP-SMRTFL plus an expression vector encoding the amino-acids 1025–1526 (RD3) or 1025–1861 (RD3–4) of SMRT or a control plasmid (encoding ß ...
Francesc X. Soriano (350148)   +1 more
core   +1 more source

„Jsem jiný, jsem slaný… a umřu dříve“ (dítě/žák s cystickou fibrózou v edukačním prostředí)

open access: yesPedagogická Orientace, 2018
V současném pojetí společného vzdělávání může učitel vykonávat přímou pedagogickou činnost v diverzní společnosti „různých“ žáků. Mezi nimi mohou být rovněž žáci a žákyně s cystickou fibrózou (CF). Jde o nevyléčitelné, progredující a smrtelné onemocnění,
Jan Chrastina   +2 more
doaj  

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.

open access: yesPLoS ONE, 2019
Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) and the nuclear receptor co-repressor1 (NCoR1) are paralogs and regulate nuclear receptor (NR) function through the recruitment of a multiprotein complex that includes histone ...
Hiroaki Shimizu   +10 more
doaj   +1 more source

miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene. [PDF]

open access: yesPLoS ONE, 2012
The signaling pathways associated with the Toll-like receptors (TLRs) and nuclear factor-kappaB (NF-κB) are essential to pro-inflammatory cytokine and chemokine expression, as well as initiating innate epithelial immune responses. The TLR/NF-κB signaling
Rui Zhou   +5 more
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines-3

open access: yes, 2011
Copyright information:Taken from "Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines"http://
David Huntsman (11166)   +7 more
core   +1 more source

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