Results 11 to 20 of about 82,646 (283)

Innovations in Snake Venom-Derived Therapeutics: A Systematic Review of Global Patents and Their Pharmacological Applications [PDF]

open access: yesToxins
Active compounds from natural sources, particularly snake venoms, are crucial for pharmaceutical development despite challenges in drug discovery. Snake venoms, historically used for medicinal purposes, contain bioactive peptides and enzymes that show ...
Diana Carolina Zona Rubio   +2 more
doaj   +2 more sources

Emerging Trends in Snake Venom-Loaded Nanobiosystems for Advanced Medical Applications: A Comprehensive Overview [PDF]

open access: yesPharmaceutics
Advances in medical nanobiotechnology have notably enhanced the application of snake venom toxins, facilitating the development of new therapies with animal-derived toxins.
Álisson E. F. Alves   +10 more
doaj   +2 more sources

A Review of the Proteomic Profiling of African Viperidae and Elapidae Snake Venoms and Their Antivenom Neutralisation

open access: yesToxins, 2022
Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans.
Benedict C. Offor   +2 more
doaj   +1 more source

Snake venom ophthalmia [PDF]

open access: yesMedical Journal Armed Forces India, 2015
Snake venom ophthalmia is caused by venoms of spitting elapid and other snakes. The cobra is one of the most venomous snakes of genus Naja. There are more than 20 species of cobra like the King cobra of South Africa, Thailand, Burma, China, India, Malaysia, Philippines; the spitting cobra of Africa and parts of South East Asia; the Indian cobra found ...
Vijay Kumar, Sharma, V K, Baranwal
openaire   +2 more sources

Snake Venom Instability [PDF]

open access: yesZoologica Africana, 1978
Comparative electrophoretic studies were conducted on the venom of the rinkals (Hemachatus haemachatus). Egyptian cobra Naja haje haje) and puffadder (Bills arietans). Considerable differences in electrophoretic characteristics were found between fresh venom and commercial venom samples from the same species of snake.
Willemse, GT, Hattingh, J.
openaire   +2 more sources

Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]

open access: yes, 2020
Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B.   +12 more
core   +1 more source

Endogenous asymmetric dimethylarginine accumulation contributes to the suppression of myocardial mitochondrial biogenesis in type 2 diabetic rats

open access: yesNutrition & Metabolism, 2020
Background Suppressed mitochondrial biosynthesis has been reported to be the early signal of mitochondrial dysfunction which contributes to diabetic cardiomyopathy, but the mechanism of mitochondrial biosynthesis suppression is unclear.
Yan Xiong   +5 more
doaj   +1 more source

Using yeast two-hybrid system and molecular dynamics simulation to detect venom protein-protein interactions

open access: yesCurrent Research in Toxicology, 2021
Proteins and peptides are major components of snake venom. Venom protein transcriptomes and proteomes of many snake species have been reported; however, snake venom complexity (i.e., the venom protein-protein interactions, PPIs) remains largely unknown ...
Ying Jia, Paulina Kowalski, Ivan Lopez
doaj   +1 more source

Venom Ophthalmia and Ocular Complications Caused by Snake Venom

open access: yesToxins, 2020
Little is known about the detailed clinical description, pathophysiology, and efficacy of treatments for ocular envenoming (venom ophthalmia) caused by venom of the spitting elapid and other snakes, as well as ocular complications caused by snake venom ...
Kun-Che Chang   +5 more
doaj   +1 more source

Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom. [PDF]

open access: yes, 2014
Attempts to reconstruct the evolutionary history of snake toxins in the context of their co-option to the venom gland rarely account for nonvenom snake genes that are paralogous to toxins, and which therefore represent important connectors to ancestral ...
Bastos, Carolina Mancini Val   +5 more
core   +3 more sources

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