Results 11 to 20 of about 173,214 (325)

Pharmacokinetics of Snake Venom [PDF]

Toxins, 2018
Understanding snake venom pharmacokinetics is essential for developing risk assessment strategies and determining the optimal dose and timing of antivenom required to bind all venom in snakebite patients. This review aims to explore the current knowledge
Suchaya Sanhajariya, S. Duffull, G. Isbister   +2 more
semanticscholar   +4 more sources

Symposium on Snake Venom [PDF]

The American Journal of the Medical Sciences, 1903
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Simon Flexner, WARFIELD T. LONGCOPE, F. P. GAY   +2 more
openalex   +4 more sources

Snake Venom Gland Organoids [PDF]

Cell, 2020
Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types. Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids that recapitulate essential features of the pertinent epithelium. Here, we establish long-term expanding venom gland organoids from several snake species.
Yorick Post, Jens Puschhof, J. Beumer, Harald M. I. Kerkkamp, M. D. Bakker, Julien Slagboom, B. D. Barbanson, N. Wevers, Xandor M. Spijkers, T. Olivier, Taline D Kazandjian, S. Ainsworth, C. L. Iglesias, Willine J. van de Wetering, Maria C Heinz, Ravian L. van Ineveld, R. Kleef, H. Begthel, J. Korving, Y. Bar-Ephraim, W. Getreuer, Anne C. Rios, R. Westerink, H. Snippert, A. Oudenaarden, P. Peters, F. Vonk, J. Kool, M. Richardson, N. Casewell, H. Clevers   +30 more
semanticscholar   +9 more sources

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, 2023
Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system
Benedict C Offor, L. Piater
semanticscholar   +1 more source

The chemistry of snake venom and its medicinal potential

Nature Reviews Chemistry, 2022
The fascination and fear of snakes dates back to time immemorial, with the first scientific treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt. Owing to their lethality, snakes have often been associated with images
Ana L. Oliveira, M. Viegas, S. L. Da Silva, A. Soares, M. Ramos, P. Fernandes   +5 more
semanticscholar   +1 more source

Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from Bothrops pictus (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and Induces Cytokine Secretion in Epithelial and Stromal Cell Lines

Pharmaceutics, 2023
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration.
Dan E. Vivas-Ruiz, Paola Rosas, Alex Proleón, Daniel Torrejón, Fanny Lazo, Ana Belén Tenorio-Ricca, Francisco Guajardo, Cristopher Almarza, Víctor Andrades, Jessica Astorga, Daniel Oropesa, Jorge Toledo, María Jesús Vera, Jorge Martínez, Ramiro Araya-Maturana, Karen Dubois-Camacho, Marcela A. Hermoso, Valéria G. Alvarenga, Eladio Flores Sanchez, Armando Yarlequé, Luciana Souza Oliveira, Félix A. Urra   +21 more
doaj   +1 more source

Investigating Toxin Diversity and Abundance in Snake Venom Proteomes

Frontiers in Pharmacology, 2022
Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development.
Theo Tasoulis, T. Pukala, G. Isbister
semanticscholar   +1 more source

Leucism and albinism in the rear-fanged snakes Tachymenis chilensis chilensis (Schlegel, 1837) and Tachymenis chilensis coronellina Werner, 1898 (Serpentes, Dipsadidae) [PDF]

Herpetozoa, 2021
Herein, we report the first observation of two different coloration patterns in Chilean snakes. Based on the alteration of wild coloration patterns, a juvenile specimen of Tachymenis chilensis coronellina Werner, 1898 was diagnosed with albinism and a ...
Felix A. Urra, Alejandro Zúñiga, Nel Melero, Nibaldo Reyes, Yarela Herrera, Alejandro Bruno Miranda-Calle, Juan Carlos Ortiz   +6 more
doaj   +3 more sources

Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins

BMC Biology, 2022
Background The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system.
B. Xie, D. Dashevsky, D. Rokyta, P. Ghezellou, B. Fathinia, Qiong Shi, M. Richardson, B. Fry   +7 more
semanticscholar   +1 more source

The Toxic Components and the Clinical Uses of Snake Venom: A Review [PDF]

Asia Pacific Journal of Medical Toxicology, 2021
Background: The venom of different snake species has a distinctive composition. This composition can be also affected by other factors such as age, sex, geographical, and seasonal variations.
Sareh Dortaj
doaj   +1 more source