Interrogating the Venom of the Viperid Snake Sistrurus catenatus edwardsii by a Combined Approach of Electrospray and MALDI Mass Spectrometry. [PDF]
PLoS ONE, 2015 The complete sequence characterization of snake venom proteins by mass spectrometry is rather challenging due to the presence of multiple isoforms from different protein families.
Alex Chapeaurouge +8 more
doaj +8 more sources
Pharmaceutics, 2023 From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration.
Dan E. Vivas-Ruiz +21 more
doaj +1 more source
Snake venom toxins: Potential anticancer therapeutics
Journal of Applied Toxicology, 2023 Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system
Benedict C Offor, L. Piater
semanticscholar +1 more source
An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells
Frontiers in Oncology, 2022 Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a promising target for new anticancer strategies.
Félix A. Urra +9 more
doaj +1 more source
Leucism and albinism in the rear-fanged snakes Tachymenis chilensis chilensis (Schlegel, 1837) and Tachymenis chilensis coronellina Werner, 1898 (Serpentes, Dipsadidae) [PDF]
Herpetozoa, 2021 Herein, we report the first observation of two different coloration patterns in Chilean snakes. Based on the alteration of wild coloration patterns, a juvenile specimen of Tachymenis chilensis coronellina Werner, 1898 was diagnosed with albinism and a ...
Felix A. Urra +6 more
doaj +3 more sources
Investigating Toxin Diversity and Abundance in Snake Venom Proteomes
Frontiers in Pharmacology, 2022 Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development.
Theo Tasoulis, T. Pukala, G. Isbister
semanticscholar +1 more source
The rise of genomics in snake venom research: recent advances and future perspectives
GigaScience, 2022 Snake venoms represent a danger to human health, but also a gold mine of bioactive proteins that can be harnessed for drug discovery purposes.
Wei-Qiao Rao +13 more
semanticscholar +1 more source
The Toxic Components and the Clinical Uses of Snake Venom: A Review [PDF]
Asia Pacific Journal of Medical Toxicology, 2021 Background: The venom of different snake species has a distinctive composition. This composition can be also affected by other factors such as age, sex, geographical, and seasonal variations.
Sareh Dortaj
doaj +1 more source
Old World Vipers—A Review about Snake Venom Proteomics of Viperinae and Their Variations
Toxins, 2021 Fine-tuned by millions of years of evolution, snake venoms have frightened but also fascinated humanity and nowadays they constitute potential resources for drug development, therapeutics and antivenoms.
Maik Damm +2 more
semanticscholar +1 more source
Snake Venom Components: Tools and Cures to Target Cardiovascular Diseases
Molecules, 2021 Cardiovascular diseases (CVDs) are considered as a major cause of death worldwide. Therefore, identifying and developing therapeutic strategies to treat and reduce the prevalence of CVDs is a major medical challenge.
Jacinthe Frangieh +6 more
semanticscholar +1 more source