Results 11 to 20 of about 23,714 (241)

Innovations in Snake Venom-Derived Therapeutics: A Systematic Review of Global Patents and Their Pharmacological Applications [PDF]

open access: yesToxins
Active compounds from natural sources, particularly snake venoms, are crucial for pharmaceutical development despite challenges in drug discovery. Snake venoms, historically used for medicinal purposes, contain bioactive peptides and enzymes that show ...
Diana Carolina Zona Rubio   +2 more
doaj   +2 more sources

Emerging Trends in Snake Venom-Loaded Nanobiosystems for Advanced Medical Applications: A Comprehensive Overview [PDF]

open access: yesPharmaceutics
Advances in medical nanobiotechnology have notably enhanced the application of snake venom toxins, facilitating the development of new therapies with animal-derived toxins.
Álisson E. F. Alves   +10 more
doaj   +2 more sources

The Role of Snake Venom Proteins in Inducing Inflammation Post-Envenomation: An Overview on Mechanistic Insights and Treatment Strategies [PDF]

open access: yesToxins
The intricate combination of organic and inorganic compounds found in snake venom includes proteins, peptides, lipids, carbohydrates, nucleotides, and metal ions.
Sudharshan Rao   +3 more
doaj   +2 more sources

A Review of the Proteomic Profiling of African Viperidae and Elapidae Snake Venoms and Their Antivenom Neutralisation

open access: yesToxins, 2022
Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans.
Benedict C. Offor   +2 more
doaj   +1 more source

The structure of His‐tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a `spanner in the works'

open access: yesActa Crystallographica Section F, Volume 78, Issue 12, Page 416-422, December 2022., 2022
The structure of Geobacillus stearothermophilus purine nucleoside phosphorylase, an enzyme of biocatalytic interest, is reported and was found to include the presence of an N‐terminal tag in the active site of each subunit that belongs to the other subunit in each dimer.
Fiona M. Given   +6 more
wiley   +1 more source

Endogenous asymmetric dimethylarginine accumulation contributes to the suppression of myocardial mitochondrial biogenesis in type 2 diabetic rats

open access: yesNutrition & Metabolism, 2020
Background Suppressed mitochondrial biosynthesis has been reported to be the early signal of mitochondrial dysfunction which contributes to diabetic cardiomyopathy, but the mechanism of mitochondrial biosynthesis suppression is unclear.
Yan Xiong   +5 more
doaj   +1 more source

Interrogating the Venom of the Viperid Snake Sistrurus catenatus edwardsii by a Combined Approach of Electrospray and MALDI Mass Spectrometry. [PDF]

open access: yesPLoS ONE, 2015
The complete sequence characterization of snake venom proteins by mass spectrometry is rather challenging due to the presence of multiple isoforms from different protein families.
Alex Chapeaurouge   +8 more
doaj   +1 more source

Plant community trajectories following livestock exclusion for conservation vary and hinge on initial invasion and soil‐biocrust conditions in shrub steppe

open access: yesConservation Science and Practice, Volume 4, Issue 12, December 2022., 2022
Following the withdrawal of livestock grazing, cheatgrass increased appreciably to surpass critical invasion thresholds. However, much can be learned from patchiness in the invasion, most notably that soil‐surface biocrusts and perennial grasses provide resistance to invasion.
Matthew J. Germino   +2 more
wiley   +1 more source

Perceptions and uses of pangolins (Pholidota) among remote rural communities in the Republic of the Congo: A baseline study from the Odzala‐Kokoua National Park

open access: yesConservation Science and Practice, Volume 4, Issue 12, December 2022., 2022
Our research focused on collecting baseline information that revealed the knowledge about species ecology and perceived market value and uses of pangolins by local communities. We identified significant differences in this data corresponding to the respondents' sociodemographic and cultural status across the surveyed villages around the Odzala‐Kokoua ...
Markéta Swiacká   +3 more
wiley   +1 more source

Bites of Venomous Snakes

open access: yesNew England Journal of Medicine, 2002
At least 2000 persons are bitten by venomous snakes in the United States each year. This article reviews the diagnosis and management of bites from venomous snakes encountered in North America, but the same principles apply to management of snakebites elsewhere in the world.
Robert A. Barish   +2 more
openaire   +7 more sources

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