Results 21 to 30 of about 170,298 (283)

The Toxic Components and the Clinical Uses of Snake Venom: A Review [PDF]

Asia Pacific Journal of Medical Toxicology, 2021
Background: The venom of different snake species has a distinctive composition. This composition can be also affected by other factors such as age, sex, geographical, and seasonal variations.
Sareh Dortaj
doaj   +1 more source

The rise of genomics in snake venom research: recent advances and future perspectives

GigaScience, 2022
Snake venoms represent a danger to human health, but also a gold mine of bioactive proteins that can be harnessed for drug discovery purposes.
Wei-Qiao Rao, K. Kalogeropoulos, M. Allentoft, Shyam Gopalakrishnan, Wei-Ning Zhao, C. Workman, Cecilie Knudsen, Belén Jiménez-Mena, Lorenzo Seneci, Mahsa Mousavi-Derazmahalleh, T. Jenkins, Esperanza Rivera-de-Torre, Si-Qi Liu, A. H. Laustsen   +13 more
semanticscholar   +1 more source

Old World Vipers—A Review about Snake Venom Proteomics of Viperinae and Their Variations

Toxins, 2021
Fine-tuned by millions of years of evolution, snake venoms have frightened but also fascinated humanity and nowadays they constitute potential resources for drug development, therapeutics and antivenoms.
Maik Damm, Benjamin-Florian Hempel, R. Süssmuth   +2 more
semanticscholar   +1 more source

Snake Venom Components: Tools and Cures to Target Cardiovascular Diseases

Molecules, 2021
Cardiovascular diseases (CVDs) are considered as a major cause of death worldwide. Therefore, identifying and developing therapeutic strategies to treat and reduce the prevalence of CVDs is a major medical challenge.
Jacinthe Frangieh, M. Rima, Z. Fajloun, D. Henrion, J. Sabatier, C. Legros, C. Mattei   +6 more
semanticscholar   +1 more source

A Review of the Proteomic Profiling of African Viperidae and Elapidae Snake Venoms and Their Antivenom Neutralisation

Toxins, 2022
Snakebite envenoming is a neglected tropical disease (NTD) that results from the injection of snake venom of a venomous snake into animals and humans.
Benedict C. Offor, Beric Muller, Lizelle A. Piater   +2 more
doaj   +1 more source

Plicidentine and the repeated origins of snake venom fangs

Proceedings of the Royal Society B, 2021
Snake fangs are an iconic exemplar of a complex adaptation, but despite striking developmental and morphological similarities, they probably evolved independently in several lineages of venomous snakes.
A. Palci, A. Leblanc, O. Panagiotopoulou, S. Cleuren, Hyab Mehari Abraha, M. Hutchinson, A. Evans, M. Caldwell, Michael S. Y. Lee   +8 more
semanticscholar   +1 more source

Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros [PDF]

, 2010
This study describes the discovery and characterisation of a novel aminopeptidase A from the venom of B. g. rhinoceros and highlights its potential biological importance.
A Addlagatta, A Moriyama, A Reaux, AG Leslie, B Nocek, BN Porto, C Claperon, DM Nanus, DN Perkins, DT Jones, DT Jones, E Gasparello-Clemente, E Quevillon, E. Gail Hutchinson, EM Danielsen, G Vazeux, G Vazeux, IM Francischetti, J Wang, JJ Calvete, JM Gibbins, John Pius Dalton, Jonathan M. Gibbins, JW Fox, K Ito, KA Kantardjieff, Kimberley A. Watson, L Anderson, L Kall, LJ McGuffin, M Migaud, MA Faiz, MA Larkin, MA Marti-Renom, MM Bradford, MM Thunnissen, N Tamura, NM Hooper, OJ Kyrieleis, P Evans, PC Rudberg, PG Laustsen, Q Wu, R Rozenfeld, R Rozenfeld, R Rozenfeld, RA Laskowski, RM Bennett-Lovsey, Robert A. Harrison, S Marchio, S McGowan, S Vaiyapuri, Sakthivel Vaiyapuri, SD Aird, SD Aird, Simon C. Wagstaff, TG Burland, VL Pham, X Iturrioz, Y Goto, Y Goto, Y Ogawa, Y Ogawa, Y Ogawa   +63 more
core   +8 more sources

Endogenous asymmetric dimethylarginine accumulation contributes to the suppression of myocardial mitochondrial biogenesis in type 2 diabetic rats

Nutrition & Metabolism, 2020
Background Suppressed mitochondrial biosynthesis has been reported to be the early signal of mitochondrial dysfunction which contributes to diabetic cardiomyopathy, but the mechanism of mitochondrial biosynthesis suppression is unclear.
Yan Xiong, Chun-Xia Hai, Wei-Jin Fang, Yan-Ping Lei, Xiao-Mei Li, Xin-Ke Zhou   +5 more
doaj   +1 more source

Before‐after‐control‐impact field experiment shows anti‐predator netting enhances occupancy of the threatened Hungarian meadow viper (Vipera ursinii rakosiensis)

Wildlife Biology, EarlyView., 2023
The Hungarian meadow viper is an endangered grassland‐dwelling species, which faces high predation pressure, partially due to avian species that forage in its habitat. Predation pressure by avian predators is caused not only by abundant game species (e.g. hooded crow, Corvus cornix) but also by protected and threatened species (e.g.
Edvárd Mizsei, Mátyás Budai, Bálint Wenner, Gergő Rák, Dávid Radovics, Barnabás Bancsik, Gergő Kovács, Ádám Tisza, János Simics, Márton Szabolcs, Csaba Vadász, Attila Móré   +11 more
wiley   +1 more source

Amplification of Snake Venom Toxicity by Endogenous Signaling Pathways

Toxins, 2020
The active components of snake venoms encompass a complex and variable mixture of proteins that produce a diverse, but largely stereotypical, range of pharmacologic effects and toxicities.
P. Bickler
semanticscholar   +1 more source