A Contemporary Exploration of Traditional Indian Snake Envenomation Therapies
Tropical Medicine and Infectious Disease, 2022 Snakebite being a quick progressing serious situation needs immediate and aggressive therapy. Snake venom antiserum is the only approved and effective treatment available, but for selected snake species only.
Adwait M. Deshpande +2 more
doaj +1 more source
Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]
, 2017 Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard +12 more
core +1 more source
Robotic modeling of snake traversing large, smooth obstacles reveals stability benefits of body compliance [PDF]
Royal Society Open Science (2020), 7, 191192, 2020 Snakes can move through almost any terrain. Although their locomotion on flat surfaces using planar gaits is inherently stable, when snakes deform their body out of plane to traverse complex terrain, maintaining stability becomes a challenge. On trees and desert dunes, snakes grip branches or brace against depressed sand for stability.
arxiv +1 more source
Development of Nanobodies Against Hemorrhagic and Myotoxic Components of Bothrops atrox Snake Venom
Frontiers in Immunology, 2020 Snake envenoming is a globally neglected public health problem. Antivenoms produced using animal hyperimmune plasma remain the standard therapy for snakebites.
Henri Bailon Calderon +18 more
semanticscholar +1 more source
bioRxiv, 2020 Animal-derived antivenoms are the only specific therapies currently available for the treatment of snake envenoming, but these products have a number of limitations associated with their efficacy, safety and affordability for use in tropical snakebite ...
Chunfang Xie +6 more
semanticscholar +1 more source
Snake antivenom for snake venom induced consumption coagulopathy [PDF]
, 2015 Background Snake venom induced consumption coagulopathy is a major systemic effect of envenoming. Observational studies suggest that antivenom improves outcomes for venom induced consumption coagulopathy in some snakebites and not others. However, the
Allen +18 more
core +1 more source
Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox [PDF]
, 2020 Snakebite envenomation causes over 140,000 deaths every year predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases.
Bicknell, Andrew B. +12 more
core +1 more source
Interior point search for nonparametric image segmentation [PDF]
, 2021 Precise object boundary detection for automatic image segmentation is critical for image analysis, including that used in computer-aided diagnosis. However, such detection traditionally uses active contour or snake models requiring accurate initialization and parameter optimization.
arxiv +1 more source
Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom. [PDF]
, 2014 Attempts to reconstruct the evolutionary history of snake toxins in the context of their co-option to the venom gland rarely account for nonvenom snake genes that are paralogous to toxins, and which therefore represent important connectors to ancestral ...
Bastos, Carolina Mancini Val +5 more
core +1 more source
Toxins, 2016 Venom detection is crucial for confirmation of envenomation and snake type in snake-bite patients. Enzyme immunoassay (EIA) is used to detect venom, but antivenom in samples prevents venom detection.
Kalana P. Maduwage +3 more
doaj +1 more source