Results 211 to 220 of about 51,201 (249)

Snake Venom Matrix Metalloproteinases (svMMPs)

2021
Inácio L. M. Junqueira-de-Azevedo, Juan David Bayona-Serrano   +1 more
openaire   +1 more source

A Novel P-III Metalloproteinase from Bothrops barnetti Venom Degrades Extracellular Matrix Proteins, Inhibits Platelet Aggregation, and Disrupts Endothelial Cell Adhesion via α5β1 Integrin Receptors to Arginine–Glycine–Aspartic Acid (RGD)-Containing Molecules

Toxins
Viperid snake venoms are notably abundant in metalloproteinases (proteins) (SVMPs), which are primarily responsible for inducing hemorrhage and disrupting the hemostatic process and tissue integrity in envenomed victims.
P. H. C. Schluga, Debora Larangote, Ana Maria de Melo, Guilherme Kamienski Lobermayer, D. Torrejón, Luciana Souza de Oliveira, V. Alvarenga, D. Vivas-Ruiz, S. S. Veiga, E. F. Sanchez, L. H. Gremski   +10 more
semanticscholar   +1 more source

Snake Optimizer: A novel meta-heuristic optimization algorithm

Knowledge-Based Systems, 2022
Abdelazim G Hussien
exaly  

Purified Zymogens Reveal Mechanisms of Snake Venom Metalloproteinase Auto-Activation

bioRxiv
Sophie Hall, Iara A. Cardoso, Mark C Wilkinson, Maria Molina Carretero, Srikanth Lingappa, Bronwyn Rand, Dakang Shen, Johara Boldrini-França, Richard Stenner, Stefanie K. Menzies, Georgia Balchin, K. Hus, R. Vincentelli, Andrew Mumford, N. Casewell, Imre Berger, C. Schaffitzel   +16 more
semanticscholar   +1 more source

Unveiling the peptidome diversity of Lachesismuta snake venom: Discovery of novel fragments of metalloproteinase, l-amino acid oxidase, and bradykinin potentiating peptides.

Biochemical and Biophysical Research Communications - BBRC, 2023
L. T. Ito, J. G. Miyamoto, S. Sant'Anna, K. Grego, A. M. Tanaka-Azevedo, Alexandre K. Tashima   +5 more
semanticscholar   +1 more source

Design and Characterization of Anticancer Peptides Derived from Snake Venom Metalloproteinase Library

International Journal of Peptide Research and Therapeutics
S. Saranya, M. Bharathi, N. S. Kumar, P. Chellapandi   +3 more
semanticscholar   +1 more source

Site mutation of residues in a loop surrounding the active site of a PI snake venom metalloproteinase abrogates its hemorrhagic activity.

Biochemical and Biophysical Research Communications - BBRC, 2019
Erika Camacho, T. Escalante, K. Remans, J. Gutiérrez, A. Rucavado   +4 more
semanticscholar   +1 more source

Local and systemic effects of BtaMP-1, a new weakly hemorrhagic snake venom metalloproteinase purified from Bothriopsis taeniata snake venom.

International Journal of Biological Macromolecules, 2019
F. Torres-Huaco, S. Maruñak, P. Teibler, S. Bustillo, O. Acosta de Pérez, L. Leiva, L. Ponce-Soto, S. Marangoni   +7 more
semanticscholar   +1 more source

A Review and Database of Snake Venom Proteomes

Toxins, 2017
Geoff K Isbister
exaly  

Betulinic, oleanolic and ursolic acids inhibit the enzymatic and biological effects induced by a P-I snake venom metalloproteinase.

Chemico-Biological Interactions, 2018
L. Preciado, P. Rey-Suárez, I. Henao, J. A. Pereañez   +3 more
semanticscholar   +1 more source