Results 51 to 60 of about 18,946 (244)

A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite

open access: yesFrontiers in Pharmacology, 2019
Snakebite is a neglected tropical disease that causes 138,000 deaths each year. Neurotoxic snake venoms contain small neurotoxins, including three-finger toxins (3FTxs), which can cause rapid paralysis in snakebite victims by blocking postsynaptic ...
Laura-Oana Albulescu   +13 more
doaj   +1 more source

Long-term health effects perceived by snakebite patients in rural Sri Lanka: A cohort study.

open access: yesPLoS Neglected Tropical Diseases, 2022
The acute effects of snakebite are often emphasized, with less information on long-term effects. We aimed to describe the long-term health effects perceived by patients followed up after confirmed snakebites.
Subodha Waiddyanatha   +4 more
doaj   +1 more source

What is the impact of snakebite envenoming on domestic animals? A nation-wide community-based study in Nepal and CameroonRecommendations

open access: yesToxicon: X, 2021
Snakebite envenoming is a life-threatening disease in humans and animals and a major public health issue in rural communities of South-East Asia and sub-Saharan Africa. Yet the impact of snakebite on domestic animals has been poorly studied.
Isabelle Bolon   +14 more
doaj   +1 more source

Hidden in Plain Sight: The Enduring Challenge of Neglected Tropical Diseases in Khartoum State, Sudan [PDF]

open access: yesJournal of Tropical Medicine
Background Neglected tropical diseases (NTDs) disproportionately affect impoverished populations in tropical regions. Despite their significant health burden, data on NTD prevalence and distribution are limited in many areas, including Khartoum State, Sudan.
Rahamtalla B.
europepmc   +2 more sources

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar   +2 more
wiley   +1 more source

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults) [PDF]

open access: gold, 2022
Michael Abouyannis   +19 more
openalex   +1 more source

Patterns and Outcomes of Poisoning Among Older Adults in Thailand: A Four‐Year Retrospective Analysis From the Siriraj Poison Control Center

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Poisoning among older adults poses unique challenges due to age‐related physiological changes, polypharmacy, and comorbidities. As Thailand transitions to a super‐aged society, this study characterizes poisoning patterns in Thai older adults to inform prevention strategies.
Pornchanok Monkaew   +3 more
wiley   +1 more source

Current Status and Influencing Factors of Snakebite Diagnosis and Treatment Knowledge Among Medical Staff in China: A Cross-Sectional Study

open access: yesInternational Journal of Public Health, 2023
Objectives: This study aimed to determine the current status of the knowledge of diagnosis and treatment of snakebites among medical staff in China and its influencing factors.Methods: A cross-sectional survey of 12,581 medical staff was conducted in 12 ...
Yanlan Hu   +16 more
doaj   +1 more source

Early treatment with intranasal neostigmine reduces mortality in a mouse model of Naja naja (Indian Cobra) envenomation [PDF]

open access: yes, 2014
Objective. Most snakebite deaths occur prior to hospital arrival; yet inexpensive, effective, and easy to administer out-of-hospital treatments do not exist. Acetylcholinesterase inhibitors can be therapeutic in neurotoxic envenomations when administered
Bickler, Philip   +5 more
core   +3 more sources

A hospital based epidemiological study of snakebite in Paschim Medinipur district, West Bengal, India

open access: yesToxicology Reports, 2017
Objective: Snakebite is a serious medical problem in Paschim Medinipur district, West Bengal, India. In the present study, hospital based data on snakebite cases and deaths were collected from 10 blocks of the district to obtain a picture of this ...
Sumana Sarkhel   +3 more
doaj   +1 more source

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