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Studies on yeast SNARE complex formation
2014In the secretory pathway of eukaryotic cells transport between membranous organelles is largely mediated by transport vesicles. One of the main unsolved questions in the field of membrane trafficking is what determines transport vesicle targeting specificity?
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Mechanisms of SNARE proteins in membrane fusion
Nature Reviews Molecular Cell Biology, 2023Reinhard Jahn, Lukas K Tamm
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Phase separation drives SNARE complexes formation
AbstractBackgroundNeuronal exocytosis is mainly driven by the assembly of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes. However, little is known about the organization principle of the SNARE complex.MethodsProtein condensates formed by SNARE complex were imaged by confocal microscope. Fluorescence recoveryFeng Chen +16 more
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Chaperoning SNARE Folding and Assembly
Annual Review of Biochemistry, 2021Yongli Zhang, Frederick M Hughson
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Why are SNARE complexes rod-shaped?
Biophysical Journal, 2022Jin Zeng +2 more
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Chaperoning SNARE assembly and disassembly
Nature Reviews Molecular Cell Biology, 2016Frederick M Hughson
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Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis
Nature, 2015Qiangjun Zhou, Ying Lai, Minglei Zhao
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The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis
Nature, 2017Qiangjun Zhou +2 more
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