Results 1 to 10 of about 74,745 (203)

A Model of Lipid Monolayer–Bilayer Fusion of Lipid Droplets and Peroxisomes

open access: yesMembranes, 2022
Lipid droplets are unique organelles that store neutral lipids encapsulated by the lipid monolayer. In some processes of cellular metabolism, lipid droplets interact with peroxisomes resulting in the fusion of their envelopes and the formation of ...
Maksim A. Kalutsky   +2 more
doaj   +3 more sources

Influence of PLIN5 and lipid composition on lipid droplet contact sites with other organelles [PDF]

open access: yesBiochemistry and Biophysics Reports
Lipid droplets (LDs) maintain cellular lipid homeostasis through dynamic interactions with other organelles. Understanding how these contact sites form is crucial for uncovering the mechanisms of lipid exchange and signaling. In this study, we used an in
Mahsa Mohammadian   +2 more
doaj   +2 more sources

Vesicle fusion with bilayer lipid membrane controlled by electrostatic interaction

open access: yesBiochemistry and Biophysics Reports, 2017
The fusion of proteoliposomes is a promising approach for incorporating membrane proteins in artificial lipid membranes. In this study, we employed an electrostatic interaction between vesicles and supported bilayer lipid membranes (s-BLMs) to control ...
Azusa Oshima, Koji Sumitomo
doaj   +3 more sources

Investigation of the Impact of Lipid Acyl Chain Saturation on Fusion Peptide Interactions with Lipid Bilayers

open access: yesBiophysica, 2023
The interaction of many peptides with lipid bilayer membranes strongly depends on the lipid composition. Here, a study of the impact of unsaturated lipid acyl chains on the interaction of a derivative of the HIV-1 fusion peptide with lipid bilayer ...
William T. Heller, Piotr A. Zolnierczuk
doaj   +1 more source

Elucidating the Influence of Lipid Composition on Bilayer Perturbations Induced by the N-Terminal Region of the Huntingtin Protein

open access: yesBiophysica, 2023
Understanding the membrane interactions of the N-terminal 17 residues of the huntingtin protein (HttN) is essential for unraveling its role in cellular processes and its impact on huntingtin misfolding. In this study, we used atomic force microscopy (AFM)
Yasith Indigahawela Gamage, Jianjun Pan
doaj   +1 more source

Investigation of Fusion between Nanosized Lipid Vesicles and a Lipid Monolayer Toward Formation of Giant Lipid Vesicles with Various Kinds of Biomolecules

open access: yesMicromachines, 2021
We determined the properties of fusion between large unilamellar vesicles (LUVs) and the lipid monolayer by measuring the fluorescence intensity of rhodamine-conjugated phospholipids in cell-sized lipid vesicles.
Koki Kamiya   +2 more
doaj   +1 more source

SNARE proteins mediate lipid bilayer fusion [PDF]

open access: yesProceedings of the National Academy of Sciences, 1999
Lipid bilayers compartmentalize eukaryotic cells into distinct organelles. This compartmentalization allows for specialization of diverse cellular processes, from DNA polymerization to zymogen proteolysis. While the specific complement of proteins present in each organelle defines its function, there is a dynamic flux between these organelles.
J B, Bock, R H, Scheller
openaire   +2 more sources

A Versatile Suspended Lipid Membrane System for Probing Membrane Remodeling and Disruption

open access: yesMembranes, 2022
Artificial membrane systems can serve as models to investigate molecular mechanisms of different cellular processes, including transport, pore formation, and viral fusion.
Achinta Sannigrahi   +5 more
doaj   +1 more source

Synthetic Cell as a Platform for Understanding Membrane-Membrane Interactions

open access: yesMembranes, 2021
In the pursuit of understanding life, model membranes made of phospholipids were envisaged decades ago as a platform for the bottom-up study of biological processes.
Bineet Sharma   +3 more
doaj   +1 more source

The Interaction of the Transmembrane Domain of SARS-CoV-2 E-Protein with Glycyrrhizic Acid in Lipid Bilayer

open access: yesMembranes, 2023
The interaction of the transmembrane domain of SARS-CoV-2 E-protein with glycyrrhizic acid in a model lipid bilayer (small isotropic bicelles) is demonstrated using various NMR techniques.
Polina A. Kononova   +2 more
doaj   +1 more source

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