Results 41 to 50 of about 74,745 (203)
Fusion of Biomimetic ‘Stealth’ Probes into Lipid Bilayer Cores [PDF]
Biophysical Journal, 2010 The ability to specifically and non-destructively incorporate inorganic structures into or through biological membranes is essential to realizing full bio-inorganic integration. However, molecular delivery and interfaces to inorganic objects, such as patch-clamp pipettes, generally rely upon destructive membrane holes and serendipitous adhesion, rather
Almquist, Ben, Melosh, Nicholas
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Mechanisms of Membrane Curvature Generation in Membrane Traffic
Membranes, 2012 During the vesicular trafficking process, cellular membranes undergo dynamic morphological changes, in particular at the vesicle generation and fusion steps.
Hye-Won Shin +2 more
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Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry
Scientific Reports, 2021 SARS-CoV-2 spike proteins are responsible for the membrane fusion event, which allows the virus to enter the host cell and cause infection. This process starts with the binding of the spike extramembrane domain to the angiotensin-converting enzyme 2 ...
Alessandra Luchini +11 more
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Frontiers in Molecular Biosciences, 2021 The fusion pore is the initial narrow connection that forms between fusing membranes. During vesicular release of hormones or neurotransmitters, the nanometer-sized fusion pore may open-close repeatedly (flicker) before resealing or dilating irreversibly,
Joerg Nikolaus +12 more
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Effect of Dengue Fusion Peptide in Anionic Lipid Bilayers [PDF]
Biophysical Journal, 2015 Studies involving peptide-induced membrane fusion are extremely important to better understanding the mechanisms underlying virus entry in cells. Particularly, membrane fusion peptides are part of Dengue virus system serving as a gateway to the virus access into the cell. Here we study the interaction of the Dengue Flavivirus fusion peptide (FLAg) with
Schmidt, Thaís F., Riske, Karin A.
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Biomolecules, 2023 Mitochondria are highly dynamic organelles that constantly undergo fusion and fission events to maintain their shape, distribution and cellular function.
Anaïs Vlieghe +5 more
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Coarse-grained simulation of amphiphilic self-assembly [PDF]
, 2007 We present a computer simulation study of amphiphilic self assembly performed using a computationally efficient single-site model based on Gay-Berne and Lennard-Jones particles. Molecular dynamics simulations of these systems show that free self-assembly
Allen M. P. +5 more
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A Dynamic Model of Fusion Pores in Lipid Bilayers [PDF]
Biophysical Journal, 2012 Biological membranes remodel and change shape in processes like endocytosis, exocytosis, hemifusion, and the expansion of fusion pores. Since the length scale of these processes is generally quite small, computational models are needed to resolve the time course of the membrane.
Ryham, Rolf +3 more
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Molecular Dynamics Investigation of Lipid-Specific Interactions with a Fusion Peptide
BiomoleculesThe HIV-1 fusion peptide, which is a short hydrophobic peptide from the gp41 coat glycoprotein that participates in the infection of a cell, interacts with model lipid bilayer membranes in a concentration-dependent manner.
William T. Heller
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Alpha-Synuclein Continues to Enhance SNARE-Dependent Vesicle Docking at Exorbitant Concentrations
Frontiers in Neuroscience, 2019 Recently, Parkinson’s disease-associated α-synuclein (αS) has emerged as an important regulator for SNARE-dependent vesicle fusion. However, it is controversial if excessive accumulation of αS, even in the absence of aggregation, impairs ...
Brenden J. D. Hawk +2 more
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