Results 61 to 70 of about 74,745 (203)

Pathway for insertion of amphiphilic nanoparticles into defect-free lipid bilayers from atomistic molecular dynamics simulations [PDF]

open access: yes, 2015
Gold nanoparticles (NPs) have been increasingly used in biological applications that involve potential contact with cellular membranes. As a result, it is essential to gain a physical understanding of NP-membrane interactions to guide the design of next ...
Alexander-Katz, Alfredo   +1 more
core   +2 more sources

Secretory and viral fusion may share mechanistic events with fusion between curved lipid bilayers [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
Activation energies for the individual steps of secretory and viral fusion are reported to be large [Oberhauser, A. F., Monck, J. R. & Fernandez, J. M. (1992) Biophys. J. 61, 800–809; Clague, M. J., Schoch, C., Zech, L. & Blumenthal, R.
J, Lee, B R, Lentz
openaire   +2 more sources

Solvent-free coarse-grained lipid model for large-scale simulations

open access: yes, 2010
A coarse-grained molecular model, which consists of a spherical particle and an orientation vector, is proposed to simulate lipid membrane on a large length scale.
Allen M. P.   +6 more
core   +1 more source

Molecular Structure Influences the Stability of Membrane Penetrating Biointerfaces. [PDF]

open access: yes, 2011
20.07.15 KB. Ok to add accepted version, 12 months embargo expired.Nanoscale patterning of hydrophobic bands on otherwise hydrophilic surfaces allows integration of inorganic structures through biological membranes, reminiscent of transmembrane proteins.
Almquist, BD, Melosh, NA
core   +1 more source

Functions of SNAREs in intracellular membrane fusion and lipid bilayer mixing [PDF]

open access: yesJournal of Cell Science, 2005
Intracellular membrane fusion occurs with exquisite coordination and specificity. Each fusion event requires three basic components: Rab-GTPases organize the fusion site; SNARE proteins act during fusion; and N-ethylmaleimide-sensitive factor (NSF) plus its cofactor α-SNAP are required for recycling or activation of the fusion machinery.
Christian, Ungermann, Dieter, Langosch
openaire   +2 more sources

Membrane partitioning of anionic, ligand-coated nanoparticles is accompanied by ligand snorkeling, local disordering, and cholesterol depletion.

open access: yesPLoS Computational Biology, 2014
Intracellular uptake of nanoparticles (NPs) may induce phase transitions, restructuring, stretching, or even complete disruption of the cell membrane.
Paraskevi Gkeka   +3 more
doaj   +1 more source

Structure formation in binary mixtures of lipids and detergents: Self-assembly and vesicle division

open access: yes, 2012
Self-assembly dynamics in binary surfactant mixtures and structure changes of lipid vesicles induced by detergent solution are studied using coarse-grained molecular simulations.
Noguchi, Hiroshi
core   +1 more source

Sensing-Applications of Surface-Based Single Vesicle Arrays

open access: yesSensors, 2010
A single lipid vesicle can be regarded as an autonomous ultra-miniaturised 3D biomimetic “scaffold” (Ø ≥ 13 nm) ideally suited for reconstitution and interrogation of biochemical processes. The enclosing lipid bilayer membrane of a vesicle can be applied
Sune M. Christensen, Dimitrios G. Stamou
doaj   +1 more source

Rapid Membrane Fusion of Individual Virus Particles with Supported Lipid Bilayers [PDF]

open access: yesBiophysical Journal, 2007
Many enveloped viruses employ low-pH-triggered membrane fusion during cell penetration. Solution-based in vitro assays in which viruses fuse with liposomes have provided much of our current biochemical understanding of low-pH-triggered viral membrane fusion.
Wessels, Laura   +3 more
openaire   +2 more sources

Transmembrane Membrane Readers form a Novel Class of Proteins That Include Peripheral Phosphoinositide Recognition Domains and Viral Spikes

open access: yesMembranes, 2022
Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time. Here, we explicate a class of proteins that contain both transmembrane and peripheral domains, which we ...
Michael Overduin   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy