Results 81 to 90 of about 74,745 (203)

Strain‐Promoted Cycloadditions in Lipid Bilayers Triggered by Liposome Fusion

Angewandte Chemie International Edition
AbstractDue to the variety of roles served by the cell membrane, its composition and structure are complex, making it difficult to study. Bioorthogonal reactions, such as the strain promoted azide‐alkyne cycloaddition (SPAAC), are powerful tools for exploring the function of biomolecules in their native environment but have been largely unexplored ...
Coline Jumeaux, Christopher D. Spicer, Patrick Charchar, Philip D. Howes, Margaret N. Holme, Li Ma, Nicholas C. Rose, Joe Nabarro, Martin A. Fascione, M. Harunur Rashid, Irene Yarovsky, Molly M. Stevens   +11 more
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Cell-Penetrating Peptides, Electroporation, and Drug Delivery

, 2010
Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis.
Cahill, Kevin
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Lysozyme interaction with negatively charged lipid bilayers: protein aggregation and membrane fusion [PDF]

Soft Matter, 2012
We report on the interaction of hen egg-white lysozyme (HEWL) with lipid vesicles in terms of surface-induced protein conformational variation and subsequent aggregation. In particular, we investigated the variations of the secondary structure of native lysozyme in the presence of liposomes with different surface charge density, resulting from ...
AL KAYAL, TAMER, NAPPINI, SILVIA, RUSSO, EDDA, BERTI, DEBORA, BUCCIANTINI, MONICA, STEFANI, MASSIMO, BAGLIONI, PIERO   +6 more
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Computational studies of biomembrane systems: Theoretical considerations, simulation models, and applications

, 2013
This chapter summarizes several approaches combining theory, simulation and experiment that aim for a better understanding of phenomena in lipid bilayers and membrane protein systems, covering topics such as lipid rafts, membrane mediated interactions ...
Deserno, Markus, Kremer, Kurt, Paulsen, Harald, Peter, Christine, Schmid, Friederike   +4 more
core   +1 more source

Structure and Topology of the Influenza Virus Fusion Peptide in Lipid Bilayers [PDF]

Journal of Biological Chemistry, 1995
The secondary structure of a 20-amino acid length synthetic peptide corresponding to the N terminus of the second subunit of hemagglutinin (HA2) of influenza virus A/PR8/34 and its interaction with phospholipid bilayers are investigated using ESR, Fourier transform infrared (FTIR), and CD spectroscopy.
Lüneberg, J, Martin, Isabelle, Nüssler, F, Ruysschaert, Jean Marie, Herrmann, A.   +4 more
openaire   +2 more sources

Variational Methods for Biomolecular Modeling

, 2016
Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs).
A Ivankin, A Jaramillo, A Warshel, AB Camley, B Lee, B Li, B Li, B Li, B Lu, B Lu, B Wang, BJ Reynwar, BR Brooks, C Mim, D Marsh, D Spoel Van Der, DG Thomas, DL Parton, E Gallicchio, E Gallicchio, EA Evans, F Campelo, FH Stillinger, FM Richards, FS Cohen, G Archontis, G-W Wei, G-W Wei, G-W Wei, GP Leser, GW Wei, HT McMahon, HY Lin, I Massova, I Park, IR Cooke, J Dzubiella, J Faraudo, J Gumbart, J Strain, J Wagoner, J Zimmerberg, JA Grant, JA Grant, JA Grant, JA Wagoner, JC Phillips, JC Stachowiak, JD Madura, JE Rothman, JMJ Swanson, K Farsad, K Lum, K Simons, KA Sharp, KM Callenberg, KS Kim, L-T Gao, LJ Pike, M Daily, M Feig, MD Huang, ME Davis, N Choudhury, N Gavish, NA Baker, NW Schmidt, O Sten-Knudsen, P Concus, P Grochowski, PB Canham, PW Bates, PW Bates, Q Du, Q Du, Q Du, Q Zheng, Q Zheng, R Brewster, R Brewster, R Parthasarathy, RA Pierotti, RE Skyner, RJ Ryham, S Choe, S Dai, S Li, S Osher, S Xu, S Zhao, S Zhao, SC Brenner, T Baumgart, T Kirchhausen, T Simonson, T Sollner, T Takahashi, T Witkowski, T-L Horng, V Luzhkov, VB Chu, W Geng, X Chen, X Chen, Y Tang, Y Wang, Y Wang, Y Wang, Y Zhao, YC Zhou, YC Zhou, Z Chen, Z Chen, Z Chen, ZY Yu   +114 more
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Plasticity of Influenza Haemagglutinin Fusion Peptides and Their Interaction with Lipid Bilayers [PDF]

Biophysical Journal, 2005
A detailed molecular dynamics study of the haemagglutinin fusion peptide (N-terminal 20 residues of the HA2 subunits) in a model bilayer has yielded useful information about the molecular interactions leading to insertion into the lipids. Simulations were performed on the native sequence, as well as a number of mutant sequences, which are either ...
Vaccaro, Loredana, Cross, Karen, Kleinjung, Jens, Strauss, Suzana, Thomas, David, Warthon, Stephen, Skehel, John, Fraternali, Franca   +7 more
openaire   +3 more sources

A novel technique using hydrophilic polymers to promote axonal fusion

Neural Regeneration Research, 2016
The management of traumatic peripheral nerve injury remains a considerable concern for clinicians. With minimal innovations in surgical technique and a limited number of specialists trained to treat peripheral nerve injury, outcomes of surgical ...
Ravinder Bamba, D Colton Riley, Nathaniel D Kelm, Mark D Does, Richard D Dortch, Wesley P Thayer   +5 more
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Implicit solvent systematic coarse-graining of dioleoylphosphatidylethanolamine lipids: From the inverted hexagonal to the bilayer structure.

PLoS ONE, 2019
Lamellar and hexagonal lipid structures are of particular importance in the biological processes such as membrane fusion and budding. Atomistic simulations of formation of these phases and transitions between them are computationally prohibitive, hence ...
Saeed Mortezazadeh, Yousef Jamali, Hossein Naderi-Manesh, Alexander P Lyubartsev   +3 more
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Phospholipid - from Model Membrane to Industrial Application

CHIMIA, 1985
The phospholipid bilayer has been shown to be a fundamental, structural element of biological membranes. An attempt is made here to briefly summarize the main physico-chemical properties of phospholipids necessary to understand their functional role in ...
Helmut Hauser
doaj   +1 more source