Rab GTPases, tethers, and SNAREs work together to regulate Arabidopsis cell plate formation
Cell plates are transient structures formed by the fusion of vesicles at the center of the dividing plane; furthermore, these are precursors to new cell walls and are essential for cytokinesis.
Yumei Shi +3 more
doaj +1 more source
Regulation of plasma membrane expansion during axon formation [PDF]
Here, will review current evidence regarding the signaling pathways and mechanisms underlying membrane addition at sites of active growth during axon formation.Fil: Quiroga, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas.
Bisbal, Mariano +2 more
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Ackermann, Frauke +5 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Only about one-third of all inferior vena cava (IVC) filters are successfully retrieved. This is largely due to factors such as IVC occlusion, filter tilt, and caval wall penetration among other reasons. IVC filter retrieval methods currently followed in
Saravanan Balachandran +3 more
doaj +1 more source
Killing Traps and Snares in North America: The Need for Stricter Checking Time Periods
In this review, we make the point that current checking times for killing traps and snares are inadequate or nonexistent in most North American jurisdictions.
Gilbert Proulx, Dwight Rodtka
doaj +1 more source
Differential Effects of Munc18s on Multiple Degranulation-Relevant Trans-SNARE Complexes. [PDF]
Mast cell exocytosis, which includes compound degranulation and vesicle-associated piecemeal degranulation, requires multiple Q- and R- SNAREs. It is not clear how these SNAREs pair to form functional trans-SNARE complexes and how these trans-SNARE ...
Hao Xu +2 more
doaj +1 more source
Status of reintroduced American marten in the Manistee National Forest within Michigan’s Northern Lower Peninsula [PDF]
American martens (Martes americana) were extirpated from the Lower Peninsula of Michigan as a result of overharvest for fur and habitat loss in the early 1900s.
Watkins, Julie M.
core +1 more source
Alternate routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4 [PDF]
Insulin-stimulated delivery of glucose transporters (GLUT4) from specialized intracellular GLUT4 storage vesicles (GSVs) to the surface of fat and muscle cells is central to whole-body glucose.
Bryant, Nia J. +3 more
core +3 more sources

