Drosophila SNAP-29 is an essential SNARE that binds multiple proteins involved in membrane traffic. [PDF]
Each membrane fusion event along the secretory and endocytic pathways requires a specific set of SNAREs to assemble into a 4-helical coiled-coil, the so-called trans-SNARE complex.
Hao Xu +4 more
doaj +1 more source
Golgi-associated retrograde protein (GARP) is an evolutionary conserved heterotetrameric protein complex that tethers endosome-derived vesicles and is vital for Golgi glycosylation. Microscopy and proteomic approaches were employed to investigate defects
Amrita Khakurel +4 more
doaj +1 more source
News and Views into the SNARE Complexity in Arabidopsis
Secretory organelles are engaged in a continuous flux of membranes, which is believed to occur mostly via transport vesicles. Being critical in maintaining several cellular functions, transport vesicles are membrane-enclosed sacs that temporarily store ...
Sang-Jin eKim +4 more
doaj +1 more source
Numerical Experiments with Coupled Membranes and the Snare Mechanism [PDF]
National audienceThe snare drum is one of the more complex musical instruments from a modeling and synthesis perspective---it includes elements modeled as 0D (the drum stick), 1D (the snares), 2D (a pair of membranes) and 3D (the cavity and perhaps the ...
Bilbao, Stefan
core +1 more source
SNARE VTI13 plays a unique role in endosomal trafficking pathways associated with the vacuole and is essential for cell wall organization and root hair growth in arabidopsis [PDF]
Background and Aims: Root hairs are responsible for water and nutrient uptake from the soil and their growth is responsive to biotic and abiotic changes in their environment.
Domozych, David S. +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Selectivity and injury risk in an improved neck snare for live‐capture of foxes
Neck snares have been considered valuable for the control of canids and to catch canids for scientific purposes, but they have been criticized for perceived low target selectivity and poor animal‐welfare. In 2006, we designed an experimental passive neck
Mike J. Short +3 more
doaj +1 more source
In search of phylogenetic congruence between molecular and morphological data in bryozoans with extreme adult skeletal heteromorphy [PDF]
peerreview_statement: The publishing and review policy for this title is described in its Aims & Scope. aims_and_scope_url: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=tsab20© Crown Copyright 2015.
Abigail M. Smith +42 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source

