Results 21 to 30 of about 44,688 (302)

The nuts and bolts of the platelet release reaction

open access: yesPlatelets, 2017
Secretion is essential to many of the roles that platelets play in the vasculature, e.g., thrombosis, angiogenesis, and inflammation, enabling platelets to modulate the microenvironment at sites of vascular lesions with a myriad of bioactive molecules ...
Smita Joshi, Sidney W. Whiteheart
doaj   +1 more source

Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]

open access: yes, 2015
Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine   +2 more
core   +2 more sources

Anthropogenic impacts to the recovery of the Mexican gray wolf with a focus on trapping‐related incidents

open access: yesWildlife Society Bulletin, 2013
Concerns regarding the potential negative impacts of regulated furbearer trapping to reintroduced Mexican gray wolves (Canis lupus baileyi), led to an executive order prohibiting trapping in the New Mexico, USA, portion of the Blue Range Wolf Recovery ...
Trey T. Turnbull   +2 more
doaj   +1 more source

Successful Use of Neck Snares to Live-Capture Red Foxes

open access: yesHuman-Wildlife Interactions, 2017
Box traps and foot-hold snares are common methods to live-capture study animals. However, these methods are frequently ineffective due to factors such as weather constraints, food availability, and target animal behavior.
S. Nicole Frey   +2 more
doaj   +1 more source

Preliminary assessment of illegal hunting by communities adjacent to the northern Gonarezhou National Park, Zimbabwe [PDF]

open access: yes, 2011
Illegal hunting of wildlife is a major issue in today’s society, particularly in tropical ecosystems. In this study, a total of 114 local residents from eight villages located in four wards adjacent to the northern Gonarezhou National Park, south-eastern
Gandiwa, E.
core   +3 more sources

Fusogenic pairings of vesicle-associated membrane proteins (VAMPs) and plasma membrane t-SNAREs--VAMP5 as the exception. [PDF]

open access: yesPLoS ONE, 2010
Intracellular vesicle fusion is mediated by the interactions of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins on vesicles (v-SNAREs) and on target membranes (t-SNAREs).
Nazarul Hasan, Deborah Corbin, Chuan Hu
doaj   +1 more source

Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering

open access: yeseLife, 2021
Membrane fusion requires R-, Qa-, Qb-, and Qc-family SNAREs that zipper into RQaQbQc coiled coils, driven by the sequestration of apolar amino acids. Zippering has been thought to provide all the force driving fusion.
Hongki Song   +4 more
doaj   +1 more source

The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. [PDF]

open access: yes, 2016
Cell polarity and precise subcellular protein localization are pivotal to neuronal function. The SNARE machinery underlies intracellular membrane fusion events, but its role in neuronal polarity and selective protein targeting remain unclear.
Albertolle, Mary E   +7 more
core   +1 more source

Wildlife hunting by indigenous people in a Philippine protected area: a perspective from Mt. Apo National Park, Mindanao Island

open access: yesJournal of Threatened Taxa, 2017
Indigenous people play a major role in the conservation of wildlife species in protected areas.  This paper provides an insight on the involvement of indigenous people in protecting and hunting of wildlife species in Mt.
Krizler Cejuela Tanalgo
doaj   +1 more source

The complementary roles of VAMP-2, -3, and -7 in platelet secretion and function

open access: yesPlatelets, 2023
Platelet secretion requires Soluble N-ethylmaleimide Sensitive Attachment Protein Receptors (SNAREs). Vesicle SNAREs/Vesicle-Associated Membrane Proteins (v-SNAREs/VAMPs) on granules and t-SNAREs in plasma membranes mediate granule release. Platelet VAMP
Smita Joshi   +5 more
doaj   +1 more source

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