Results 181 to 190 of about 3,204 (201)

Voriconazole-loaded self-nanoemulsifying drug delivery system (SNEDDS) to improve transcorneal permeability

Pharmaceutical Development and Technology, 2020
The aim of this study was to develop self- nanoemulsifying drug delivery system (SNEDDS) to improve the transcorneal permeability of voriconazole. A 'mixture design around a reference mixture' approach was applied. This latter included four components, namely, isopropyl myristate, PEG 400, Tween® 80 and Span® 80 as oil, co-solvent, surfactant and co ...
Bakoliarisoa Nivomalala Voahangy, Rasoanirina, Mohamed Ali, Lassoued, Amel, Kamoun, Badr, Bahloul, Karim, Miladi, Souad, Sfar   +5 more
openaire   +2 more sources

Performance of oral Bosentan-loaded SNEDDS and S-SNEDDS tablets: Biodistribution in mice, echocardiography and histology studies in pulmonary arterial hypertension rat model

European Journal of Pharmaceutics and Biopharmaceutics
Bosentan monohydrate (BOS) is the most preferred molecule for treating the rare pulmonary arterial hypertension (PAH) disease. BOS shows low solubility and high variability when administered orally. This study evaluated the pharmacodynamic biodistribution, echocardiography, and histology results of BOS-loaded SNEDDS and BOS-loaded S-SNEDDS tablets ...
Duygu YILMAZ USTA, Seval OLGAC, Murside Ayse DEMIREL, Serdar KULA, Cigdem ELMAS, Perihan SEZGINER, Akif KAVGACI, Zeynep Safak TEKSIN   +7 more
openaire   +2 more sources

3D printed capsule shells for personalized dosing of cyclosporine-loaded SNEDDS

International Journal of Pharmaceutics
Cyclosporine (CsA) is a potent immunosuppressant agent that has been used since 1980 for the treatment of various autoimmune diseases and is extensively used to enhance the survival rate of patients and grafts following organ transplant surgeries. CsA is a poorly soluble drug with a narrow therapeutic window and inter-subject variability, which can ...
Mohammed S. Algahtani, Abdul Aleem Mohammed, Javed Ahmad, Raisuddin Ali, Ehab Saleh   +4 more
openaire   +2 more sources

Fortifying SNEDDS with Hybrid Technologies: Present and Future Prospects

Current Nanomedicine
Self-nano-emulsifying drug delivery systems (SNEDDS) have gained attention in recentyears as an effective approach for improving the solubility and oral bioavailability of poorlywater-soluble drugs. However, there have been reports of drawbacks such as low drug loading,limited stability and variability in ...
Nithya Shanthi, Khushbu Arora, Himani Pant, Komal Soni, Geetika Gupta, Gaurav Chandra, Arun Kumar Mahato   +6 more
openaire   +1 more source

Self-nanoemulsifying drug delivery systems (SNEDDS) - influences on cellular uptake

2017
The field of nanocarriers for drug delivery has developed rapidly over the last decades. Recently the innovative approach of self-emulsifying systems has caught researcher's interest. The aim of this study was to investigate influences on cellular uptake of self-nanoemulsifying drug delivery systems (SNEDDS) with regard to droplet size and the presence
openaire   +1 more source

Unveiling the dielectric properties of self-nanoemulsifying drug delivery systems (SNEDDS)

Journal of Molecular Liquids, 2023
D.A. Bravo Alfaro, E. Prokhorov, G. Luna Barcenas, H.S. García   +3 more
openaire   +1 more source

Advancements in SNEDDS

Manjot Kaur, Seweta Srivastava, Samir Mehndiratta, Rajeev Kumar   +3 more
openaire   +1 more source

SNEDDS in MMU

2019
openaire   +1 more source

Characterization Techniques for SNEDDS

Aditi Dubal, Srushti Mahajan, Nandkishor Rajankar, Mayur Aalhate, Indrani Maji, Ujala Gupta, Pankaj Kumar Singh   +6 more
openaire   +1 more source

Formulation Components of SNEDDS

Sambhav Sharma, Sunidhi Saini, Mehak Sharma, Aniket Sharma, Sachin Kumar Singh, Narendra Kumar Pandey   +5 more
openaire   +1 more source