Results 91 to 100 of about 14,550 (176)

The regulatory roles of small nucleolar RNAs within their host locus

RNA Biology
Small nucleolar RNAs (snoRNAs) are a class of conserved noncoding RNAs forming complexes with proteins to catalyse site-specific modifications on ribosomal RNA. Besides this canonical role, several snoRNAs are now known to regulate diverse levels of gene
Étienne Fafard-Couture, Stéphane Labialle, Michelle S Scott   +2 more
doaj   +1 more source

Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer.

PLoS ONE, 2014
BackgroundThe growth arrest-specific transcript 5 gene (GAS5) encodes a long noncoding RNA (lncRNA) and hosts a number of small nucleolar RNAs (snoRNAs) that have recently been implicated in multiple cellular processes and cancer.
Jonathan Krell, Adam E Frampton, Reza Mirnezami, Victoria Harding, Alex De Giorgio, Laura Roca Alonso, Patrizia Cohen, Silvia Ottaviani, Teresa Colombo, Jimmy Jacob, Loredana Pellegrino, Gordon Buchanan, Justin Stebbing, Leandro Castellano   +13 more
doaj   +1 more source

ctDNA SNORD3F Hypermethylation is a Prognostic Indicator in EGFR-TKI-Treated Advanced Non-Small Cell Lung Cancer

Cancer Management and Research
Bin Liu,* Bingtian Zhao,* Yan Yin, Yan Jiang, Xue Feng, Lei Wang, Liang Zhai, Guangxin Liu, Dongsheng Shi, Jianwen Qin Department of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, People’s Republic of China*These authors ...
Liu B, Zhao B, Yin Y, Jiang Y, Feng X, Wang L, Zhai L, Liu G, Shi D, Qin J   +9 more
doaj  

Integrative analysis of a novel snoRNA-based prognostic signature in patients with breast cancer

Frontiers in Oncology
BackgroundBreast cancer (BC) is the most commonly diagnosed malignancy in women worldwide. Prognostic heterogeneity driven by molecular subtypes and tumor microenvironment underscores the need for novel biomarkers.
Yi Xun, Xia-hui Li, Wen-tao Xiao, Jun-yan He   +3 more
doaj   +1 more source

Knock-Down of a Novel snoRNA in Tetrahymena Reveals a Dual Role in 5.8S rRNA Processing and Generation of a 26S rRNA Fragment

Biomolecules, 2018
In eukaryotes, 18S, 5.8S, and 28S rRNAs are transcribed as precursor molecules that undergo extensive modification and nucleolytic processing to form the mature rRNA species. Central in the process are the small nucleolar RNAs (snoRNAs).
Kasper L. Andersen, Henrik Nielsen
doaj   +1 more source

EV-derived small non-coding RNAs from porcine follicular fluid regulate follicle development using Pandora sequence. [PDF]

Front Vet Sci
Hu J, Peng S, Deng W, Guo Z, Wu J, Tan X, Zeng Z, Wang A.   +7 more
europepmc   +1 more source

Advances in the study of nucleolar small RNAs in colorectal cancer. [PDF]

iScience
Yuan Z, Chen Y, Liu S, Yang J, Tang C, He X, Wang S, Wang X.   +7 more
europepmc   +1 more source

CPF-CF-terminated snoRNAs shuttle through the cytoplasm via an mRNA guard protein-mediated surveillance mechanism. [PDF]

Nat Commun
Yu F, Zaccagnini G, Duan Y, Lamping JP, Tagnères S, Bohnsack KE, Krebber H.   +6 more
europepmc   +1 more source

A Novel snoRNA, Gm24418 Attenuates Inflammation Injury After Acute TBI Through Regulating CCL2

Journal of Inflammation Research
Ming Luo,1– 3 Yang Wang,1– 3 Xiaohang Guo,1– 3 Weikang Luo,1– 3 Zhiqiang Yuan,1– 3 Xueping Yang,1– 3 Xudong Fan,1– 3 Zhaoyu Yang,1– 3 Tao Tang1– 3 1Department of Integrated Traditional Chinese and Western Medicine, Institute of Integrative Medicine ...
Luo M, Wang Y, Guo X, Luo W, Yuan Z, Yang X, Fan X, Yang Z, Tang T   +8 more
doaj  

Quantitative analysis of small RNA pseudouridylation reveals interplay of PUS enzymes in tRNA anticodon stem-loop. [PDF]

Nat Commun
Liu W, Ma Y, Wang L, Lu B, Dong Y, Zhuang Y, He B, Zhang M, Yi C.   +8 more
europepmc   +1 more source