Results 71 to 80 of about 14,550 (176)

Analysis of Human Small Nucleolar RNAs (snoRNA) and the Development of snoRNA Modulator of Gene Expression Vectors [PDF]

Molecular Biology of the Cell, 2010
Human small nucleolar RNAs (snoRNAs) that copurify with nucleoli isolated from HeLa cells have been characterized. Novel fibrillarin-associated snoRNAs were detected that allowed the creation of a new vector system for the targeted knockdown of one or more genes in mammalian cells.
Ono, Motoharu, Yamada, Kayo, Avolio, Fabio, Scott, Michelle S., van Koningsbruggen, Silvana, Barton, Geoffrey J., Lamond, Angus I.   +6 more
openaire   +3 more sources

Splicing-related features of introns serve to propel evolution. [PDF]

PLoS ONE, 2013
The role of spliceosomal intronic structures played in evolution has only begun to be elucidated. Comparative genomic analyses of fungal snoRNA sequences, which are often contained within introns and/or exons, revealed that about one-third of snoRNA ...
Yuping Luo, Chun Li, Xi Gong, Yanlu Wang, Kunshan Zhang, Yaru Cui, Yi Eve Sun, Siguang Li   +7 more
doaj   +1 more source

Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study examined the translation activity across ten stages of maize anther development, integrating transcriptome and small‐peptide data. It linked mutations in translated 3' ORFs to anther sterility, exemplified by Zm00001eb417050_3' ORF (known as APV1). In addition, the data indicated that maize anthers could assimilate CO2 through the stomata in
Chunyu Wang, Yuechao Wu, Shunxi Wang, Han Liu, Siqi Jiang, Yingjia Han, Liuji Wu, Tao Zhang, Mei Zhang   +8 more
wiley   +1 more source

Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing [PDF]

Genome Biology, 2013
Abstract Background In recent years, a variety of small RNAs derived from other RNAs with well-known functions such as tRNAs and snoRNAs, have been identified. The functional relevance of these RNAs is largely unknown.
Kishore, Shivendra, Gruber, Andreas R., Jedlinski, Dominik J., Syed, Afzal P., Jorjani, Hadi, Zavolan, Mihaela   +5 more
openaire   +3 more sources

Transcriptional repressor NIR functions in the ribosome RNA processing of both 40S and 60S subunits. [PDF]

PLoS ONE, 2012
BACKGROUND: NIR was identified as an inhibitor of histone acetyltransferase and it represses transcriptional activation of p53. NIR is predominantly localized in the nucleolus and known as Noc2p, which is involved in the maturation of the 60S ribosomal ...
Jianguo Wu, Ying Zhang, Yingshuang Wang, Ruirui Kong, Lelin Hu, Roland Schuele, Xiaojuan Du, Yang Ke   +7 more
doaj   +1 more source

Metamorphosis and lncRNAs: A Close Relationship

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The classical definition of metamorphosis is a post‐embryonic transformation, such as from a tadpole to a froglet. However, recent studies suggest this process occurs to some degree in all vertebrates, as the underlying endocrine and molecular pathways are highly conserved. With the advent of high‐throughput sequencing, transcriptomic data for
H. Herrera‐Orozco, H. A. Pérez‐Mendoza   +1 more
wiley   +1 more source

SnoReport: computational identification of snoRNAs with unknown targets [PDF]

Bioinformatics, 2007
AbstractSummary: Unlike tRNAs and microRNAs, both classes of snoRNAs, which direct two distinct types of chemical modifications of uracil residues, have proved to be surprisingly difficult to find in genomic sequences. Most computational approaches so far have explicitly used the fact that snoRNAs predominantly target ribosomal RNAs and spliceosomal ...
Hertel, Jana, Hofacker, Ivo L., Stadler, Peter F.   +2 more
openaire   +4 more sources

Genomic Analysis and Population Divergence Driven by Geographic Isolation in Neotetracus sinensis

Ecology and Evolution, Volume 16, Issue 4, April 2026.
We generated the first chromosome‐level reference genome for Neotetracus sinensis and resequenced populations from the Gaoligong and Wuliang Mountains to investigate divergence across the Hengduan “sky‐island” landscape. Genomic data reveal strong population structure with negligible gene flow and parallel demographic histories shaped by Pleistocene ...
Jianxuan Zhou, Nannan Chen, Weihao Dou, Zhonglai Luo, Libo Jiang, Meidong Jing, Fengtang Yang   +6 more
wiley   +1 more source

The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa [PDF]

Nucleic Acids Research, 2003
Using a powerful computer-assisted analysis strategy, a large-scale search of small nucleolar RNA (snoRNA) genes in the recently released draft sequence of the rice genome was carried out. This analysis identified 120 different box C/D snoRNA genes with a total of 346 gene variants, which were predicted to guide 135 2'-O-ribose methylation sites in ...
Chun-Long, Chen, Dan, Liang, Hui, Zhou, Min, Zhuo, Yue-Qin, Chen, Liang-Hu, Qu   +5 more
openaire   +2 more sources

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source