Results 61 to 70 of about 14,550 (176)

Highly heterozygous Citrus changshan‐huyou Y. B. Chang originated from ancient hybridization between mandarin and pummelo and displayed distinct tissue‐specific allelic imbalance

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng, Yingjie Luo, Haifei Hu, Lan Lan, Baojin Guo, Ping Zhou, Cong Tan, Xiaoping Huang, Tuo Qi, Zhehao Chen, Zhiming Yu, Lilin Wang, Taihe Xiang, Chengdao Li, Yong Jia   +14 more
wiley   +1 more source

Atrophic Skeletal Muscle‐Derived Extracellular Vesicles Transfer miR‐125a‐5p to Inhibit Bone Formation in Osteoporosis during Aging

Advanced Science, Volume 13, Issue 25, 4 May 2026.
A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao, Pan Zhang, Zhidan Fan, Jiaquan Lin, Xiang Chen, Na Liu, Wang Gong, Yi He, Yining Zhou, Tianshu Shi, Yong Shi, Yuze Ma, Wentian Gao, Haosheng Wang, Depeng Fang, Chengzhi Wang, Wenshu Wu, Wenjin Yan, Jianghui Qin, Dongyang Chen, Haiguo Yu, Qing Jiang, Baosheng Guo   +22 more
wiley   +1 more source

SNOntology: Myriads of novel snornas or just a mirage?

BMC Genomics, 2011
Background Small nucleolar RNAs (snoRNAs) are a large group of non-coding RNAs (ncRNAs) that mainly guide 2'-O-methylation (C/D RNAs) and pseudouridylation (H/ACA RNAs) of ribosomal RNAs.
Makarova Julia A, Kramerov Dmitri A
doaj   +1 more source

Expression and processing of a small nucleolar RNA from the Epstein-Barr virus genome. [PDF]

PLoS Pathogens, 2009
Small nucleolar RNAs (snoRNAs) are localized within the nucleolus, a sub-nuclear compartment, in which they guide ribosomal or spliceosomal RNA modifications, respectively. Up until now, snoRNAs have only been identified in eukaryal and archaeal genomes,
Roland Hutzinger, Regina Feederle, Jan Mrazek, Natalia Schiefermeier, Piotr J Balwierz, Mihaela Zavolan, Norbert Polacek, Henri-Jacques Delecluse, Alexander Hüttenhofer   +8 more
doaj   +1 more source

Intersecting Molecular Pathways in Cardiovascular Disease and Diabetes Mellitus: Emerging Roles of Inflammation and Therapeutics

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 4, May 2026.
Central illustration: Pathophysiological mechanisms linking diabetes mellitus and cardiovascular disease. Chronic hyperglycaemia, insulin resistance, and low‐grade inflammation contribute to endothelial dysfunction, myocardial fibrosis, and cardiomyocyte apoptosis.
Lilian Anagnostopoulou, Nikolaos Ktenopoulos, Anastasios Apostolos, Christos Fragoulis, Panayotis Vlachakis, Paschalis Karakasis, Marios Sagris, Nikias Milaras, Maria Drakopoulou, Andreas Synetos, Ioannis Kyriazis, Ioannis Ioannidis, Costas Tsioufis, Konstantinos Toutouzas   +13 more
wiley   +1 more source

Exercise and Skeletal Muscle‐Derived Extracellular Vesicles: Their Cargo, Release, and Role in Metabolic Regulation

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT The health benefits of exercise are well established in the prevention and management of metabolic disorders such as obesity and diabetes. Emerging evidence indicates that extracellular vesicles (EVs) may contribute to the beneficial effects of exercise.
Jeremy Boulestreau, Scott K. Ferguson, Luke Nelson, Noemi Polgar   +3 more
wiley   +1 more source

Saturated Fatty Acids and snoRNAs: Partners in Crime [PDF]

Cell Metabolism, 2011
Lipotoxicity describes the process of cellular dysfunction in response to lipid overload. In this issue of Cell Metabolism, Michel and colleagues (2011) provide evidence for a role of snoRNAs in palmitate-induced oxidative stress.
Mattijssen, F.B.J., Kersten, A.H.
openaire   +3 more sources

SNORA14A inhibits hepatoblastoma cell proliferation by regulating SDHB-mediated succinate metabolism

Cell Death Discovery, 2023
Hepatoblastoma (HB) is the most common paediatric liver malignancy. Dysregulation of small nucleolar RNAs (snoRNAs) is a critical inducer of tumour initiation and progression. However, the association between snoRNAs and HB remains unknown.
Jiabei Zhu, Siwei Mao, Ni Zhen, Guoqing Zhu, Zhixuan Bian, Yi Xie, Xiaochen Tang, Miao Ding, Han Wu, Ji Ma, Yizhun Zhu, Fenyong Sun, Qiuhui Pan   +12 more
doaj   +1 more source

The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia

International Journal of Cancer, Volume 158, Issue 8, Page 2003-2012, 15 April 2026.
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch, Ana Carolina Rodrigues, Priscila Elias Ferreira Stricker, Alexandre Luiz Korte Azevedo, Daniel Pacheco Bruschi, Jaqueline Carvalho de Oliveira   +5 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, Volume 600, Issue 8, Page 1248-1262, April 2026.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source