Results 61 to 70 of about 15,041 (173)

snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs [PDF]

Nucleic Acids Research, 2006
The snoRNA-LBME-db is a dedicated database containing human C/D box and H/ACA box small nucleolar RNAs (snoRNAs), and small Cajal body-specific RNAs (scaRNAs). C/D box and H/ACA box snoRNAs are part of ribonucleoparticles that guide 2'-O-ribose methylation and pseudouridilation, respectively, of selected residues of 28S, 18S or 5.8S rRNAs or of the ...
Laurent Lestrade, Michel J. Weber
openaire   +2 more sources

Accurate identification of snoRNA targets using variational graph autoencoder to advance the redevelopment of traditional medicines

Frontiers in Pharmacology
Existing studies indicate that dysregulation or abnormal expression of small nucleolar RNA (snoRNA) is closely associated with various diseases, including lung cancer.
Zhina Wang, Zhina Wang, Yangyuan Chen, Hongming Ma, Hongming Ma, Hong Gao, Hong Gao, Yangbin Zhu, Hongwu Wang, Nan Zhang, Nan Zhang   +10 more
doaj   +1 more source

SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights

BMC Genomics, 2009
Background SnoRNAs represent an excellent model for studying the structural and functional evolution of small non-coding RNAs involved in the post-transcriptional modification machinery for rRNAs and snRNAs in eukaryotic cells.
Chen Chun-Long, Yang Jian-Hua, Guan Dao-Gang, Liang Yin-Tong, Shao Peng, Yu Chun-Hong, Xiao Zhen-Dong, Liu Na, Qu Liang-Hu, Zhou Hui   +9 more
doaj   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Intronic small nucleolar RNAs regulate host gene splicing through base pairing with their adjacent intronic sequences

Genome Biology, 2023
Background Small nucleolar RNAs (snoRNAs) are abundant noncoding RNAs best known for their involvement in ribosomal RNA maturation. In mammals, most expressed snoRNAs are embedded in introns of longer genes and produced through transcription and splicing
Danny Bergeron, Laurence Faucher-Giguère, Ann-Kathrin Emmerichs, Karine Choquet, Kristina Sungeun Song, Gabrielle Deschamps-Francoeur, Étienne Fafard-Couture, Andrea Rivera, Sonia Couture, L. Stirling Churchman, Florian Heyd, Sherif Abou Elela, Michelle S. Scott   +12 more
doaj   +1 more source

Extracellular Vesicle‐Encapsulated Small RNAs From Clostridium Butyricum Modulate Host Intestinal Lipid Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Extracellular vesicles (EVs) derived from C. butyricum can enter intestinal epithelial cells and mediate the anti‐lipid absorption effects by delivering miRNA‐like RNAs (milRNAs), particularly milRNA‐3020179, which primarily targeted host genes majorly including PPARα. Deletion of milRNA‐3020179 in C. butyricum abolished its effects on lipid deposition
Hong Hu, Yiwen He, Jing Liang, Qi Han, Xuqing Liang, Guangtian Cao, Yulong Tang, Liuqin He, Yulong Yin, Xihong Zhou   +9 more
wiley   +1 more source

Network of epistatic interactions within a yeast snoRNA [PDF]

Science, 2016
Epistasis and mutational fitness landscapeA fitness landscape of a gene defines the molecular potential of evolution. This can help us understand the current state of evolution as well as predict unrealized potential. Using deep sequencing to examine mutations in nonessential genes that affect the growth of yeast strains, two studies have generated ...
Puchta, O., Cseke, B., Czaja, H., Tollervey, D., Sanguinetti, G., Kudla, G.   +5 more
openaire   +4 more sources

Emerging Data on the Diversity of Molecular Mechanisms Involving C/D snoRNAs

Non-Coding RNA, 2021
Box C/D small nucleolar RNAs (C/D snoRNAs) represent an ancient family of small non-coding RNAs that are classically viewed as housekeeping guides for the 2′-O-methylation of ribosomal RNA in Archaea and Eukaryotes.
Laeya Baldini, Bruno Charpentier, Stéphane Labialle   +2 more
doaj   +1 more source

Evaluating Plasma‐Handling Effects on Extracellular Vesicle RNA Yield and Cargo Profiles in Fish: A Methodological Insight

Journal of Extracellular Biology, Volume 5, Issue 10, October 2026.
Experimental Design Overview Illustration to visualize the experimental structure (can be included in a graphical abstract later on)—Diagram / Workflow showing fish plasma collection, sample conditions: (a) volume groups (1 mL vs 2 mL or Midi vs Maxi); (b) Fresh vs frozen EV isolation→RNA extraction→Sequencing pipeline.
Antonio Espuela‐Ortiz, Estrella Antón‐González, Louis Bonnefous, M. Virginia Martín, Salvador Jeréz, Deiene Rodríguez‐Barreto   +5 more
wiley   +1 more source

A Csi‐miR3954b‐CsCE70/CsPLA1 Regulatory Module Enhances Citrus Fruit Resistance to Penicillium digitatum by Promoting Phenolic Acid and Flavonoid Biosynthesis

Molecular Plant Pathology, Volume 27, Issue 10, October 2026.
Csi‐miR3954b targets CsCE70 and CsPLA1, promoting the synthesis of phenolic acids and flavonoids, thereby enhancing citrus resistance to postharvest green mould. ABSTRACT Green mould is one of the major postharvest diseases affecting citrus. Although evidence indicates that microRNAs (miRNAs) participate in plant defence responses, their roles and ...
Jixin Tian, Xiaoquan Gao, Jialin Chen, Kuo Meng, Ou Chen, Wenjun Wang, Lanhua Yi, Kaifang Zeng   +7 more
wiley   +1 more source