Results 41 to 50 of about 15,041 (173)

Comparative analysis of eukaryotic U3 snoRNA [PDF]

RNA Biology, 2009
The U3 snoRNA is an exceptional box C/D snoRNA, which is involved in pre-rRNA processing without directing chemical modifications. We report here on a comprehensive computational survey resulting in U3 sequences for more than 90 additional eukaryotes. This extended data basis is used to improve the secondary structure models. The detailed investigation
Marz, Manja, Stadler, Peter F.
openaire   +3 more sources

Small Nucleolar RNAs in Pseudoexfoliation Glaucoma

Cells, 2022
Small nucleolar RNAs (snoRNAs) are small non-coding regulatory RNAs that have been investigated extensively in recent years. However, the relationship between snoRNA and glaucoma is still unknown.
Karolina Gasińska, Marcin Czop, Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Janusz Kocki, Tomasz Żarnowski   +5 more
doaj   +1 more source

Long Noncoding RNAs with snoRNA Ends [PDF]

Molecular Cell, 2012
We describe the discovery of sno-lncRNAs, a class of nuclear-enriched intron-derived long noncoding RNAs (lncRNAs) that are processed on both ends by the snoRNA machinery. During exonucleolytic trimming, the sequences between the snoRNAs are not degraded, leading to the accumulation of lncRNAs flanked by snoRNA sequences but lacking 5' caps and 3' poly(
Yin, Qing-Fei, Yang, Li, Zhang, Yang, Xiang, Jian-Feng, Wu, Yue-Wei, Carmichael, Gordon G., Chen, Ling-Ling   +6 more
openaire   +2 more sources

A Pan-cancer Analysis of the Expression and Clinical Relevance of Small Nucleolar RNAs in Human Cancer

Cell Reports, 2017
Summary: Increasing evidence has demonstrated that small nucleolar RNAs (snoRNAs) play important roles in tumorigenesis. We systematically investigated the expression landscape and clinical relevance of snoRNAs in >10,000 samples across 31 cancer types ...
Jing Gong, Yajuan Li, Chun-jie Liu, Yu Xiang, Chunlai Li, Youqiong Ye, Zhao Zhang, David H. Hawke, Peter K. Park, Lixia Diao, John A. Putkey, Liuqing Yang, An-Yuan Guo, Chunru Lin, Leng Han   +14 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Non-coding snoRNA host genes in Drosophila: expression strategies for modification guide snoRNAs

European Journal of Cell Biology, 2001
Modification guide snoRNAs either are encoded within introns and co-transcribed with the host gene pre-mRNA or are independently transcribed as mono- or polycistronic units. Different eukaryotic kingdoms utilize these coding strategies to various degrees.
K T, Tycowski, J A, Steitz
openaire   +2 more sources

Evolutionary profiling of the U49 snoRNA gene [PDF]

Hereditas, 2003
Small nucleolar RNAs (snoRNAs) are involved in precursor ribosomal RNA (pre-rRNA) processing and rRNA base modifications (2'-O-ribose methylation and pseudouridylation). Their genomic organization show great flexibility: some are individually or polycistronically transcribed, while others are encoded within introns of other genes.
Espen, Enerly, Oyvind L, Mikkelsen, May, Lyamouri, Andrew, Lambertsson   +3 more
openaire   +2 more sources

Mapping snoRNA-target RNA interactions in an RNA-binding protein-dependent manner with chimeric eCLIP

Genome Biology
Background Small nucleolar RNAs (snoRNAs) are non-coding RNAs that function in ribosome and spliceosome biogenesis, primarily by guiding modifying enzymes to specific sites on ribosomal RNA (rRNA) and spliceosomal RNA (snRNA).
Zhuoyi Song, Bongmin Bae, Simon Schnabl, Fei Yuan, Thareendra De Zoysa, Maureen V. Akinyi, Charlotte A. Le Roux, Karine Choquet, Amanda J. Whipple, Eric L. Van Nostrand   +9 more
doaj   +1 more source

Separated Siamese Twins: Intronic Small Nucleolar RNAs and Matched Host Genes May be Altered in Conjunction or Separately in Multiple Cancer Types

Cells, 2020
Small nucleolar RNAs (snoRNAs) are non-coding RNAs involved in RNA modification and processing. Approximately half of the so far identified snoRNA genes map within the intronic regions of host genes, and their expression, as well as the expression of ...
Marianna Penzo, Rosanna Clima, Davide Trerè, Lorenzo Montanaro   +3 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source