Results 101 to 110 of about 15,243 (207)

SnoRNAs: Exploring Their Implication in Human Diseases

International Journal of Molecular Sciences
Small nucleolar RNAs (snoRNAs) are earning increasing attention from research communities due to their critical role in the post-transcriptional modification of various RNAs. These snoRNAs, along with their associated proteins, are crucial in regulating the expression of a vast array of genes in different human diseases.
Waseem Chauhan, null Sudharshan SJ, Sweta Kafle, Rahima Zennadi   +3 more
openaire   +2 more sources

An Improved Description of the Small RNA Landscape of the Human Fungal Pathogen Aspergillus fumigatus

Molecular Microbiology, Volume 125, Issue 2, Page 133-144, February 2026.
The mechanisms of small RNA biogenesis in fungi are diverse and multifactorial. Here, we provide an improved understanding of the processing of double‐stranded RNA in the human fungal pathogen Aspergillus fumigatus, revealing susceptibility to high levels of double‐stranded RNA and limited input of the canonical RNAi machinery on the endogenous small ...
Xiaoqing Pan, Abdulrahman A. Kelani, Lukas Schrettenbrunner, Swatika Prabakar, Bhawana Israni, Matthew G. Blango   +5 more
wiley   +1 more source

Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer.

PLoS ONE, 2014
BackgroundThe growth arrest-specific transcript 5 gene (GAS5) encodes a long noncoding RNA (lncRNA) and hosts a number of small nucleolar RNAs (snoRNAs) that have recently been implicated in multiple cellular processes and cancer.
Jonathan Krell, Adam E Frampton, Reza Mirnezami, Victoria Harding, Alex De Giorgio, Laura Roca Alonso, Patrizia Cohen, Silvia Ottaviani, Teresa Colombo, Jimmy Jacob, Loredana Pellegrino, Gordon Buchanan, Justin Stebbing, Leandro Castellano   +13 more
doaj   +1 more source

Alternative Splicing of lncRNAs From SNHG Family Alters snoRNA Expression and Induces Chemoresistance in Hepatoblastoma [PDF]

, 2023
Ni Zhen, Jiabei Zhu, Siwei Mao, Qi Zhang, Song Gu, Ji Ma, Yanlong Zhang, Minzhi Yin, Haojie Li, Nan Huang, Han Wu, Fenyong Sun, Binwu Ying, Lin Zhou, Qiuhui Pan   +14 more
openalex   +1 more source

Eukaryotic snoRNAs: A paradigm for gene expression flexibility

Genomics, 2009
Small nucleolar RNAs (snoRNAs) are one of the most ancient and numerous families of non-protein-coding RNAs (ncRNAs). The main function of snoRNAs - to guide site-specific rRNA modification - is the same in Archaea and all eukaryotic lineages. In contrast, as revealed by recent genomic and RNomic studies, their genomic organization and expression ...
DIECI, Giorgio, MONTANINI, Barbara, PRETI M   +2 more
openaire   +3 more sources

The regulatory roles of small nucleolar RNAs within their host locus

RNA Biology
Small nucleolar RNAs (snoRNAs) are a class of conserved noncoding RNAs forming complexes with proteins to catalyse site-specific modifications on ribosomal RNA. Besides this canonical role, several snoRNAs are now known to regulate diverse levels of gene
Étienne Fafard-Couture, Stéphane Labialle, Michelle S Scott   +2 more
doaj   +1 more source

Knock-Down of a Novel snoRNA in Tetrahymena Reveals a Dual Role in 5.8S rRNA Processing and Generation of a 26S rRNA Fragment

Biomolecules, 2018
In eukaryotes, 18S, 5.8S, and 28S rRNAs are transcribed as precursor molecules that undergo extensive modification and nucleolytic processing to form the mature rRNA species. Central in the process are the small nucleolar RNAs (snoRNAs).
Kasper L. Andersen, Henrik Nielsen
doaj   +1 more source

Guide RNAs with 5′ Caps and Novel Box C/D snoRNA-like Domains for Modification of snRNAs in Metazoa [PDF]

, 2004
Kazimierz T. Tycowski, Alar Aab, Joan A. Steitz   +2 more
openalex   +1 more source

SnoRNAs in cardiovascular development, function, and disease

Trends in Molecular Medicine
Small nucleolar RNAs (snoRNAs) are emerging as important regulators of cardiovascular (patho)biology. Several roles of snoRNAs have recently been identified in heart development and congenital heart diseases, as well as their dynamic regulation in hypertrophic and dilated cardiomyopathies, coronary heart disease (CHD), myocardial infarction (MI ...
Alzbeta Chabronova, Terri L. Holmes, Duc M. Hoang, Chris Denning, Victoria James, James G.W. Smith, Mandy J. Peffers   +6 more
openaire   +3 more sources

ctDNA SNORD3F Hypermethylation is a Prognostic Indicator in EGFR-TKI-Treated Advanced Non-Small Cell Lung Cancer

Cancer Management and Research
Bin Liu,* Bingtian Zhao,* Yan Yin, Yan Jiang, Xue Feng, Lei Wang, Liang Zhai, Guangxin Liu, Dongsheng Shi, Jianwen Qin Department of Respiratory and Critical Medicine, Tianjin Chest Hospital, Tianjin, People’s Republic of China*These authors ...
Liu B, Zhao B, Yin Y, Jiang Y, Feng X, Wang L, Zhai L, Liu G, Shi D, Qin J   +9 more
doaj