Results 101 to 110 of about 73,771 (300)
SNP array screening of cryptic genomic imbalances in 450 Japanese subjects with intellectual disability and multiple congenital anomalies previously negative for large rearrangements [PDF]
, 2016 Daniela Tiaki Uehara +15 more
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.High‐dose methotrexate for pediatric cancer treatment is frequently associated with mucositis, which can lead to delayed or discontinued treatment and impact survival. While individual genetic variants have been implicated, the cumulative impact of genetic variation within relevant biological pathways remains unexplored.
Xiao Yu Cindy Zhang +9 more
wiley +1 more source
A reference haplotype panel for genome-wide imputation of short tandem repeats
Nature Communications, 2018 Short-tandem repeats (STR), similar to single nucleotide polymorphisms (SNP), contribute to complex traits, but their ascertainment by next-generation sequencing is costly. Here, Saini et al.
Shubham Saini +4 more
doaj +1 more source
Use of High Density Single Nucleotide Polymorphism (SNP) Arrays to Assess Genetic Diversity and Population Structure of Dairy Cattle in Smallholder Dairy Systems: The Case of Girinka Programme in Rwanda [PDF]
, 2018 M.G.G. Chagunda +5 more
openalex +1 more source
Environmental and Molecular Mutagenesis, EarlyView.Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk +4 more
wiley +1 more source
Neonatal seizures: Advances in diagnosis and management
Epilepsia Open, EarlyView.Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz +2 more
wiley +1 more source
Food Frontiers, EarlyView.This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu +12 more
wiley +1 more source
SNP-specific array-based allele-specific expression analysis [PDF]
, 2008 Hans T. Björnsson +8 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Hepatocellular carcinoma arises from a combination of environmental and genetic factors, with the latter playing a potentially more significant role in nonviral hepatocellular carcinoma. Here, the authors characterized the genetic correlations and heritability between nonviral hepatocellular carcinoma and 901 epidemiologic, behavioral, and ...
Younghun Han +37 more
wiley +1 more source
International Journal of Cancer, EarlyView.What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin +9 more
wiley +1 more source