Results 101 to 110 of about 1,520,842 (344)
Vertical Nanostructures as Novel Interfaces for Brain Research
Advanced Materials Interfaces, EarlyView.This review highlights the unique features of vertical nanostructures (nanoneedles, nanostraws, nanopillars, and nanowires) for applications in brain research. Various characteristics of nanostructures, including material selection, fabrication methodology, and geometric designs, are discussed for their specific use in neurite guidance, neuron pinning,
Hao Nguyen Tran +3 more
wiley +1 more source
Genetics Selection Evolution, 2018 High levels of pairwise linkage disequilibrium (LD) in single nucleotide polymorphism (SNP) array or whole-genome sequence data may affect both performance and efficiency of genomic prediction models.
M. Calus, J. Vandenplas
semanticscholar +1 more source
Advanced Science, EarlyView.Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa +15 more
wiley +1 more source
Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds
BMC Genomics, 2017 Background To date, genome-scale analyses in the domestic horse have been limited by suboptimal single nucleotide polymorphism (SNP) density and uneven genomic coverage of the current SNP genotyping arrays.
Robert J. Schaefer +34 more
doaj +1 more source
CropSNPdb: a database of SNP array data for Brassica crops and hexaploid bread wheat
The Plant Journal, 2019 Advances in sequencing technology have led to a rapid rise in the genomic data available for plants, driving new insights into the evolution, domestication and improvement of crops.
Armin Scheben +6 more
semanticscholar +1 more source
How Array Design affects SNP Ascertainment Bias [PDF]
, 2019 AbstractSingle nucleotide polymorphisms (SNPs), genotyped with SNP arrays, have become a widely used marker type in population genetic analyses over the last 10 years. However, compared to whole genome re-sequencing data, arrays are known to lack a substantial proportion of globally rare variants and tend to be biased towards variants present in ...
Steffen Weigend +6 more
openaire +3 more sources
The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication
Advanced Science, EarlyView.Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li +9 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2018 The heavy selection pressure due to intensive breeding of Brassica napus has created a narrow gene pool, limiting the ability to produce improved varieties through crosses between B. napus cultivars.
E. Higgins +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies the mitochondrial protein RTA9, a member of the Domain of Unknown Function 641 family, together with its partner S40, as key regulators of aphid resistance in maize. RTA9 promotes S40 degradation and modulates reactive oxygen species accumulation.
Chuanhong Wang +12 more
wiley +1 more source
Theoretical and Applied Genetics, 2015 Key messageA 20K SNP array was developed and a comprehensive set of tetraploid cultivar was genotyped. This allowed us to identify footprints of the breeding history in contemporary breeding material such as identification of introgression segments ...
P. Vos +4 more
semanticscholar +1 more source