Results 171 to 180 of about 912,126 (302)

Pediatric B-Cell Acute Lymphoblastic Leukemia: Comprehensive Genomic Characterization Including SNP-Array and Analysis of Relapse Risk. [PDF]

Cancers (Basel)
Prats-Martín C, Pérez Ortega L, Molinos Quintana Á, Ribera J, Chiclana Rodríguez B, Caballero-Velázquez T, Carrillo Cruz E, Andrade-Ruiz HA, Garrastazul Sánchez MP, Madrigal Toscano MD, Solé Rodríguez M, Gómez Rosa M, Pérez-Simón JA, Morales-Camacho RM.   +13 more
europepmc   +1 more source

Triangulating Evidence on Serum Uric Acid and Cancer Risk: Consistent Inverse Associations With Lung Cancer

Cancer Science, EarlyView.
Using both conventional observational and Mendelian randomization (MR) analyses in the same Japanese community‐dwelling population, the evidence consistently supported an inverse association between the serum uric acid level and lung cancer risk. ABSTRACT We examined the association between serum uric acid (UA) levels and cancer incidence through a ...
Takashi Matsunaga, Kenji Wakai, Takashi Tamura, Mako Nagayoshi, Rieko Okada, Itsuki Kageyama, Megumi Hara, Takuma Furukawa, Hiroaki Ikezaki, Yuji Matsumoto, Takeshi Nishiyama, Hiroko Nakagawa‐Senda, Chihaya Koriyama, Shiroh Tanoue, Naoyuki Takashima, Etsuko Ozaki, Katsuyuki Miura, Aya Kadota, Takeshi Watanabe, Masashi Ishizu, Kiyonori Kuriki, Masahiro Nakatochi, Yukihide Momozawa, Issei Imoto, Isao Oze, Keitaro Matsuo, the J‐MICC Study Group   +26 more
wiley   +1 more source

Identifying the contributions of progenitor Malus species to cultivated apple (M. domestica) using 20K SNP array data. [PDF]

BMC Genomics
Howard NP, Vanderzande S, Khan G, Luby JJ, Volk GM, Albach DC, Peace C.   +6 more
europepmc   +1 more source

A Homozygous Frameshift Variant in KHDC4 Is Associated With a Syndromic Inherited Retinal Disease in Humans

Clinical Genetics, EarlyView.
We identified a homozygous frameshift variant in KHDC4 (c.1535_1538del: (p.Lys512Argfs*8) in a consanguineous family with syndromic Retinitis Pigmentosa. Functional characterization shows aberrant protein mislocalisation from nuclear speckles to a diffuse pattern.
Asodu Sandeep Sarma, Neta Barnoy, Prakadeeswari Gopalakrishnan, Keren Dichter, Rotem Mizrachi, Manar Salameh, Eyal Banin, Dror Sharon, Adi Inbal, Samer Khateb   +9 more
wiley   +1 more source

How Are SNP-Array, Karyotyping, and FISH Applied in Prenatal Practice? A Focus on Diagnosis of Mosaicism Involving the Sex Chromosomes. [PDF]

Prenat Diagn
Luo X, Niu H, Chen X, Zhou F, Cong X, Li S, Pei Y, Chang L, Liu W, Wei F.   +9 more
europepmc   +1 more source

Budding speciation, mitochondrial capture and introgression between surface and cave lineages in the Asellus aquaticus species complex

Cladistics, EarlyView.
Abstract Replicated pairs of ancestral and evolutionarily derived populations provide opportunities to test hypotheses about the deterministic laws of evolution. The Asellus aquaticus species complex is an invertebrate model system with several independent surface‐to‐cave transitions and a complicated and unresolved evolutionary history.
Peter Trontelj, Valerija Zakšek, Anja Palandačić, Hans Recknagel   +3 more
wiley   +1 more source

Characterizing SMN1 hybrid and deletion alleles using large-scale SNP array-based SMA carrier screening. [PDF]

BMC Med Genomics
Vidal-Folch N, Stout C, Winters J, Oglesbee D, Hasadsri L, Cook SL.   +5 more
europepmc   +1 more source

Polygenic Risk Scores for Islet Autoantibody Positive Early‐Stage Type 1 Diabetes Pre‐Screening

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To develop a sex‐aligned polygenic risk score (PRS) for early‐stage type 1 diabetes (T1D) in children without a first‐degree family history of T1D. Materials and Methods Global Single Nucleotide Polymorphism (SNP) Array was performed in 16 335 individuals without a first‐degree family history of T1D, including 13 956 newborns from the ...
Jose Zapardiel‐Gonzalo, Christiane Winkler, Florian Haupt, Manja Jolink, Alexandra Käßl, Konstantinos Hatzikotoulas, Anette‐G. Ziegler, Ezio Bonifacio   +7 more
wiley   +1 more source

Development and application of a 10 K low-density whole-genome SNP array for chickens. [PDF]

Poult Sci
Ma X, Chen Y, Wang M, Bai L, Zheng M, Zhao G, Wen J, Liu R.   +7 more
europepmc   +1 more source

Equine vegetative endocarditis and vertebral osteomyelitis due to refractory Erysipelothrix rhusiopathiae infection

Equine Veterinary Education, EarlyView.
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou, Z. Daobry, Â. J. F. Mendes, G. Weller, S. Radhakrishnan, M. S. I. Sajib, M. Fuentes, F. Zendri, T. Forde, W. Weir, J. Del‐Pozo, D. G. M. Sutton   +11 more
wiley   +1 more source