Results 11 to 20 of about 75,410 (157)

Assessing the clinical application value of SNP-array in fetal central nervous system malformations [PDF]

Human Genomics
Background Single nucleotide polymorphism array (SNP-array) has been introduced for prenatal diagnosis. This study aims to evaluate the clinical utility of SNP-array in the prenatal central nervous system (CNS) malformations.
Wei Li, Jiasun Su, Weiliang Lu, Xianglian Tang, Chaofan Zhou, Yueyun Lan, Yuan Wei, Limei Huang, Jingrong Luo, Shan Ou, Shuyin Tan, Shengkai Wei, Yaoyao Jiang, Jingyu Su, Liang Wang, Minpan Huang, Jingsi Luo, Peng Huang   +17 more
doaj   +2 more sources

Deducing genotypes for loci of interest from SNP array data via haplotype sharing, demonstrated for apple and cherry. [PDF]

PLoS ONE, 2023
Breeders, collection curators, and other germplasm users require genetic information, both genome-wide and locus-specific, to effectively manage their genetically diverse plant material.
Alexander Schaller, Stijn Vanderzande, Cameron Peace   +2 more
doaj   +2 more sources

A SNP Genotyping Array for Hexaploid Oat

The Plant Genome, 2014
Recognizing a need in cultivated hexaploid oat ( L.) for a reliable set of reference single nucleotide polymorphisms (SNPs), we have developed a 6000 (6K) BeadChip design containing 257 Infinium I and 5486 Infinium II designs corresponding to 5743 SNPs ...
Nicholas A. Tinker, Shiaoman Chao, Gerard R. Lazo, Rebekah E. Oliver, Yung-Fen Huang, Jesse A. Poland, Eric N. Jellen, Peter J. Maughan, Andrzej Kilian, Eric W. Jackson   +9 more
doaj   +2 more sources

SNP+ to predict dropout rates in SNP arrays

Conservation Genetics Resources, 2022
Abstract Genotyping individuals using forensic or non-invasive samples such as hair or fecal samples increases the risk of allelic amplification failure (dropout) due to the low quality and quantity of DNA. One way to decrease genotyping errors is to increase the number of replicates per sample.
Sastre Alaiz, Natalia, Mercadé Carceller, Anna, Casellas Vidal, Joaquim   +2 more
openaire   +3 more sources

Clinical Utility of SNP Array Analysis in Prenatal Diagnosis: A Cohort Study of 5000 Pregnancies

Frontiers in Genetics, 2020
BackgroundSingle nucleotide polymorphism array (SNP-array) has been introduced for prenatal diagnosis. We aimed to evaluate the clinical value of SNP-array in the diagnosis of fetal chromosomal anomalies.MethodsA retrospective study was conducted on 5000
Jingjing Xiang, Jingjing Xiang, Yang Ding, Yang Ding, Xiaoyan Song, Xiaoyan Song, Jun Mao, Jun Mao, Minjuan Liu, Minjuan Liu, Yinghua Liu, Yinghua Liu, Chao Huang, Chao Huang, Qin Zhang, Qin Zhang, Ting Wang, Ting Wang   +17 more
doaj   +1 more source

TAFFYS: An Integrated Tool for Comprehensive Analysis of Genomic Aberrations in Tumor Samples. [PDF]

PLoS ONE, 2015
Tumor single nucleotide polymorphism (SNP) array is a common platform for investigating the cancer genomic aberration and the functionally important altered genes.
Yuanning Liu, Ao Li, Huanqing Feng, Minghui Wang   +3 more
doaj   +1 more source

Detection rates of abnormalities in over 10,000 amniotic fluid samples at a single laboratory

BMC Pregnancy and Childbirth, 2023
Background A growing number of cytogenetic techniques have been used for prenatal diagnosis. This study aimed to demonstrate the usefulness of karyotyping, BACs-on-Beads (BoBs) assay and single nucleotide polymorphism (SNP) array in prenatal diagnosis ...
Sha Lu, Nisile Kakongoma, Wen-sheng Hu, Yan-zhen Zhang, Nan-nan Yang, Wen Zhang, Ai-fen Mao, Yi Liang, Zhi-fen Zhang   +8 more
doaj   +1 more source

Novel Design of Imputation-Enabled SNP Arrays for Breeding and Research Applications Supporting Multi-Species Hybridization

Frontiers in Plant Science, 2021
Array-based single nucleotide polymorphism (SNP) genotyping platforms have low genotype error and missing data rates compared to genotyping-by-sequencing technologies.
Gabriel Keeble-Gagnère, Raj Pasam, Kerrie L. Forrest, Debbie Wong, Hannah Robinson, Jayfred Godoy, Allan Rattey, David Moody, Daniel Mullan, Tresslyn Walmsley, Hans D. Daetwyler, Hans D. Daetwyler, Josquin Tibbits, Matthew J. Hayden, Matthew J. Hayden   +14 more
doaj   +1 more source

SNP Array in Hematopoietic Neoplasms: A Review [PDF]

Microarrays, 2015
Cytogenetic analysis is essential for the diagnosis and prognosis of hematopoietic neoplasms in current clinical practice. Many hematopoietic malignancies are characterized by structural chromosomal abnormalities such as specific translocations, inversions, deletions and/or numerical abnormalities that can be identified by karyotype analysis or ...
Song, Jinming, Shao, Haipeng
openaire   +2 more sources

Integration of Infinium and Axiom SNP array data in the outcrossing species Malus × domestica and causes for seemingly incompatible calls

BMC Genomics, 2021
Background Single nucleotide polymorphism (SNP) array technology has been increasingly used to generate large quantities of SNP data for use in genetic studies.
Nicholas P. Howard, Michela Troggio, Charles-Eric Durel, Hélène Muranty, Caroline Denancé, Luca Bianco, John Tillman, Eric van de Weg   +7 more
doaj   +1 more source