Results 291 to 300 of about 1,520,842 (344)
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
ABSTRACT Missing pedigrees are a common problem in most populations. Animals with unknown ancestors are usually treated as founders; however, this can underestimate inbreeding, not properly account for different base populations, and bias breeding values.
Larissa Temp +7 more
wiley +1 more source
ABSTRACT In tropical extensive beef cattle systems, heifers raised on pasture are exposed to various environmental challenges that affect their growth and reproductive performance during the first breeding. Resilience indicators derived from deviations in longitudinal traits can quantify the magnitude of these challenges and the ability of an animal to
Gustavo R. D. Rodrigues +11 more
wiley +1 more source
Multi‐Breed Genomic Predictions for Average Daily Gain in Three Italian Beef Cattle Breeds
ABSTRACT Marchigiana, Chianina, and Romagnola are three Italian autochthonous beef cattle breeds that have been historically selected for meat production. Recent advancements suggest that the use of genomic data and multi‐breed (MB) models to combine information from different breeds may help to increase the accuracies of genomic predictions, in ...
Daniele Colombi +5 more
wiley +1 more source
ABSTRACT Indirect predictions (IP) are used for young genotyped animals that lack phenotypes (of their own or from progeny) or are from commercial herds. The former can be left behind because they do not contribute to the official genomic evaluations.
Marisol Londoño‐Gil +5 more
wiley +1 more source
ABSTRACT Indicators of heat stress response are heritable complex traits with polygenic inheritance. Copy number variations (CNV) are important genomic structural variations that may be linked to climatic adaptation by influencing the phenotypic variability of traits related to thermal stress and disease resistance in animals.
Letícia Fernanda de Oliveira +6 more
wiley +1 more source
Genomic Prediction Ability for Novel Profitability Traits Using Different Models in Nelore Cattle
ABSTRACT The aim of this study was to assess the accuracy, bias and dispersion of genomic predictions for accumulated profitability (APF) and profit per kilogram of liveweight gain (PFT) in Nelore cattle using different prediction approaches. The dataset consisted of 3969 phenotypic records for each trait. The pedigree harboured information from 38,930
Letícia Silva Pereira +9 more
wiley +1 more source
ABSTRACT In order to investigate the applicability and efficiency of genomic selection for growth and carcass traits in Nordic beef cattle, single‐step genomic BLUP (ssGBLUP) was applied in 4321 Charolais and 4532 Hereford animals with information on approximately 43,000 SNPs each.
Anahit Nazari‐Ghadikolaei +2 more
wiley +1 more source

