Results 51 to 60 of about 1,566,477 (261)
Development and validation of a 20K single nucleotide polymorphism (SNP) whole genome genotyping array for apple (Malus × domestica Borkh). [PDF]
PLoS ONE, 2014 High-density SNP arrays for genome-wide assessment of allelic variation have made high resolution genetic characterization of crop germplasm feasible. A medium density array for apple, the IRSC 8K SNP array, has been successfully developed and used for ...
Luca Bianco +14 more
doaj +1 more source
BMC Bioinformatics, 2007 Background DNA copy number aberration (CNA) is one of the key characteristics of cancer cells. Recent studies demonstrated the feasibility of utilizing high density single nucleotide polymorphism (SNP) genotyping arrays to detect CNA.
Bailey Dione K +8 more
doaj +1 more source
High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. [PDF]
, 2015 Human genome-wide association studies have identified thousands of loci associated with disease phenotypes. Genome-wide association studies also have become feasible using rodent models and these have some important advantages over human studies ...
Churchill, Gary A +6 more
core +1 more source
Genome-wide association study in two cohorts from a multi-generational mouse advanced intercross line highlights the difficulty of replication due to study-specific heterogeneity [PDF]
, 2020 There has been extensive discussion of the Replication Crisis in many fields, including genome-wide association studies
Cheng, Riyan +7 more
core +2 more sources
Localization of adaptive variants in human genomes using averaged one-dependence estimation. [PDF]
, 2018 Statistical methods for identifying adaptive mutations from population genetic data face several obstacles: assessing the significance of genomic outliers, integrating correlated measures of selection into one analytic framework, and distinguishing ...
Atkinson, Elizabeth G +5 more
core +3 more sources
Genome-wide association studies of inflammatory bowel disease in German shepherd dogs [PDF]
, 2018 Canine Inflammatory Bowel Disease (IBD) is considered a multifactorial disease caused by complex interactions between the intestinal immune system, intestinal microbiota and environmental factors in genetically susceptible individuals.
Allenspach, Karin +7 more
core +5 more sources
Clinical and Experimental Obstetrics & Gynecology, 2022 Background: This study aimed to compare the use of next-generation sequencing (NGS) and single-nucleotide polymorphism (SNP) array in preimplantation genetic testing for aneuploidy (PGT-A) in the same blastocyst.
Zhanhui Ou +3 more
doaj +1 more source
Frontiers in Genetics, 2020 High-density single-nucleotide polymorphism (SNP) genotyping array is an essential tool for genetic analyses of animals and plants. Large yellow croaker (Larimichthys crocea) is one of the most commercially important marine fish species in China ...
Tao Zhou +15 more
doaj +1 more source
Tumor Touch Imprints as Source for Whole Genome Analysis of Neuroblastoma Tumors. [PDF]
PLoS ONE, 2016 INTRODUCTION:Tumor touch imprints (TTIs) are routinely used for the molecular diagnosis of neuroblastomas by interphase fluorescence in-situ hybridization (I-FISH).
Clemens Brunner +7 more
doaj +1 more source
BMC Genomics, 2017 Runs of Homozygosity (ROH) are genomic regions where identical haplotypes are inherited from each parent. Since their first detection due to technological advances in the late 1990s, ROHs have been shedding light on human population history and ...
F. Ceballos, S. Hazelhurst, M. Ramsay
semanticscholar +1 more source