Results 151 to 160 of about 97,365 (285)

The Impact of the Rs1044457 Polymorphism in the CMPK1 Gene on the Response Rate to Gemcitabine‐Based Chemotherapy in Metastatic NSCLC Patients

open access: yesAdvanced Genetics, EarlyView.
Lung cancer is the leading cause of cancer‐related mortality worldwide. Among its types, non‐small cell lung cancer (NSCLC) accounts for the majority of cases. This study focuses on investigating genetic mutations that may influence the response to gemcitabine, a chemotherapy drug commonly used to treat this condition.
Ghassan Saod Saleh   +3 more
wiley   +1 more source

Deciphering dual clinical entities associated with TP53 pathogenic variants: Insights from 53,085 HBOC panel analyses in French laboratories

open access: yesInternational Journal of Cancer, EarlyView.
What's New? TP53 is included in most cancer predisposition multigene panels, but analyzing the contribution of TP53 variants to cancer predisposition beyond the Li–Fraumeni syndrome remains challenging. This study, based on 53,085 hereditary breast and ovarian cancer panel analyses, explores the genotype–phenotype correlation of TP53 variants and ...
Edwige Kasper   +46 more
wiley   +1 more source

RETRACTED: Genotyping strategies for tissues fixed with various embalming fluids for human identification, databasing, and traceability

open access: yesJournal of Forensic Sciences, EarlyView., 2023
Abstract Within anatomical willed body programs and skeletal collections, whole bodies and their disassociated limbs and organs are identified and tracked. However, if these tracking mechanisms fail, DNA recovered from the formalin‐fixed tissues/organs could provide an additional layer of quality assurance. Embalming fluids preserve biological tissues;
Madeline Ashton   +3 more
wiley   +1 more source

Comparison of GenFlex Tag Array and Pyrosequencing in SNP Genotyping [PDF]

open access: bronze, 2003
Daniel C. Chen   +5 more
openalex   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

A rapid, microplate SNP genotype assay for the leptinob alleles⃞

open access: yesJournal of Lipid Research, 2008
A nonsense mutation in the mouse leptin gene causes genetic obesity. As a result of extensive research in the field of obesity, the use of leptinob mice is widespread. This mutation renders mice sterile, creating the need to breed heterozygous mice.
Angie T. Oler, Alan D. Attie
doaj  

Home - About - Disclaimer - Privacy