Results 181 to 190 of about 223,459 (323)

Two Methods of Whole-Genome Amplification Enable Accurate Genotyping Across a 2320-SNP Linkage Panel [PDF]

open access: hybrid, 2004
David Barker   +13 more
openalex   +1 more source

Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar   +9 more
wiley   +1 more source

Development of a 135K SNP genotyping array for Actinidia arguta and its applications for genetic mapping and QTL analysis in kiwifruit. [PDF]

open access: yesPlant Biotechnol J, 2023
Wang R   +15 more
europepmc   +1 more source

Genotype and allele frequencies of thirty-two SNPs in the ARHGAP18 gene of schizophrenia patients and controls.

open access: green, 2017
Weiyun Guo   +10 more
openalex   +2 more sources

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2025 Update

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Thiopurine methyltransferase (TPMT) and Nudix hydrolase 15 (NUDT15) are key enzymes that catabolize thiopurines. Decreased or no‐function alleles in TPMT and NUDT15 are associated with reduced or no enzyme activity and predictive of pronounced adverse effects, including severe myelosuppression, that may occur among individuals treated with standard ...
Maud Maillard   +18 more
wiley   +1 more source

CAPS-Based SNP Genotyping for Nitrogen-Response Phenotypes in Maize Hybrids. [PDF]

open access: yesBio Protoc
Jacobs J   +6 more
europepmc   +1 more source

Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel. [PDF]

open access: yesMicrob Genom, 2021
Labbé G   +19 more
europepmc   +1 more source

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo   +11 more
wiley   +1 more source

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