Results 11 to 20 of about 219,663 (291)

Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]

BMC Genomics, 2006
Abstract Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J, Moskvina Valentina, Georgieva Lyudmila, Nikolov Ivan, Kirov George, O'Donovan Michael C   +5 more
openaire   +4 more sources

Universal probe-based intermediate primer-triggered qPCR (UPIP-qPCR) for SNP genotyping. [PDF]

BMC Genomics, 2021
Background The detection and identification of single nucleotide polymorphism (SNP) is essential for determining patient disease susceptibility and the delivery of medicines targeted to the individual.
Li B, Liu Y, Hao X, Dong J, Chen L, Li H, Wu W, Liu Y, Wang J, Wang Y, Li P.   +10 more
europepmc   +2 more sources

A multisite SNP genotyping and macrolide susceptibility gene method for Mycoplasma pneumoniae based on MALDI-TOF MS

iScience, 2021
Summary: In this study, a multisite SNP genotyping and macrolide (ML) susceptibility gene test method for Mycoplasma pneumoniae (M. pneumoniae) was developed based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF
Fei Zhao, Jianzhong Zhang, Xuemei Wang, Liyong Liu, Jie Gong, Zhixiang Zhai, Lihua He, Fanliang Meng, Di Xiao   +8 more
doaj   +1 more source

Rapid and simple SNP genotyping for Bordetella pertussis epidemic strain MT27 based on a multiplexed single-base extension assay

Scientific Reports, 2021
Multilocus variable-number tandem repeat analysis (MLVA) is widely used for genotyping of Bordetella pertussis, the causative bacteria for pertussis. However, MLVA genotyping is losing its discriminate power because prevalence of the epidemic MT27 strain
Kazunari Kamachi, Shu-Man Yao, Chuen-Sheue Chiang, Kentaro Koide, Nao Otsuka, Keigo Shibayama   +5 more
doaj   +1 more source

Comparison of sequencing-based and array-based genotyping platforms for genomic prediction of maize hybrid performance

Crop Journal, 2023
Genomic selection (GS) is a powerful tool for improving genetic gain in maize breeding. However, its routine application in large-scale breeding pipelines is limited by the high cost of genotyping platforms.
Guangning Yu, Yanru Cui, Yuxin Jiao, Kai Zhou, Xin Wang, Wenyan Yang, Yiyi Xu, Kun Yang, Xuecai Zhang, Pengcheng Li, Zefeng Yang, Yang Xu, Chenwu Xu   +12 more
doaj   +1 more source

Agrigenomic Diversity Unleashed: Current Single Nucleotide Polymorphism Genotyping Methods for the Agricultural Sciences

Applied Biosciences, 2023
Single Nucleotide Polymorphisms (SNPs) are variations that occur at single nucleotides in the genome and are present at an appreciable level in a population.
Roger D. Lawrie, Steven E. Massey
doaj   +1 more source

Imputation strategies for genomic prediction using nanopore sequencing

BMC Biology, 2023
Background Genomic prediction describes the use of SNP genotypes to predict complex traits and has been widely applied in humans and agricultural species.
H. J. Lamb, L. T. Nguyen, J. P. Copley, B. N. Engle, B. J. Hayes, E. M. Ross   +5 more
doaj   +1 more source

Detecting SARS-CoV-2 variants with SNP genotyping. [PDF]

PLoS One, 2021
Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively ...
Harper H, Burridge A, Winfield M, Finn A, Davidson A, Matthews D, Hutchings S, Vipond B, Jain N, COVID-19 Genomics UK (COG-UK) Consortium, Edwards K, Barker G.   +11 more
europepmc   +2 more sources

Genotyping by genome reducing and sequencing for outbred animals. [PDF]

PLoS ONE, 2013
Next-generation sequencing (NGS) approaches are widely used in genome-wide genetic marker discovery and genotyping. However, current NGS approaches are not easy to apply to general outbred populations (human and some major farm animals) for SNP ...
Qiang Chen, Yufang Ma, Yumei Yang, Zhenliang Chen, Rongrong Liao, Xiaoxian Xie, Zhen Wang, Pengfei He, Yingying Tu, Xiangzhe Zhang, Changsuo Yang, Hongjie Yang, Fuqing Yu, Youmin Zheng, Zhiwu Zhang, Qishan Wang, Yuchun Pan   +16 more
doaj   +1 more source

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

Malaria Journal, 2019
Background Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection.
Joseph Fulakeza, Sarah McNitt, Jimmy Vareta, Alex Saidi, Godfrey Mvula, Terrie Taylor, Don P. Mathanga, Dylan S. Small, Jacek Skarbinski, Julie R. Gutman, Karl Seydel   +10 more
doaj   +1 more source