Results 31 to 40 of about 337,686 (261)

Effect of Combining Multiple CNV Defining Algorithms on the Reliability of CNV Calls from SNP Genotyping Data [PDF]

Genomics & Informatics, 2012
In addition to single-nucleotide polymorphisms (SNP), copy number variation (CNV) is a major component of human genetic diversity. Among many whole-genome analysis platforms, SNP arrays have been commonly used for genomewide CNV discovery.
Soon-Young Kim, Ji-Hong Kim, Yeun-Jun Chung   +2 more
doaj   +1 more source

High quality genome-wide genotyping from archived dried blood spots without DNA amplification. [PDF]

PLoS ONE, 2013
Spots of blood are routinely collected from newborn babies onto filter paper called Guthrie cards and used to screen for metabolic and genetic disorders. The archived dried blood spots are an important and precious resource for genomic research.
Krystal R St Julien, Laura L Jelliffe-Pawlowski, Gary M Shaw, David K Stevenson, Hugh M O'Brodovich, Mark A Krasnow, Stanford BPD Study Group   +6 more
doaj   +1 more source

Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays. [PDF]

, 2010
Background: We report an attempt to extend the previously successful approach of combining SNP (single nucleotide polymorphism) microarrays and DNA pooling (SNP-MaP) employing high-density microarrays.
Farmer, A., Pirlo Katrina, Farmer, Anne E, Gray, J, Jones, L, Emma Meaburn (27672), Ian W Craig (16171385), Gaysina, D, Ian W Craig, Emma Meaburn, Craig, I., Korszun Ania, Cohen-Woods Sarah, Gray Joanna, Cohen-Woods, Sarah, Schalkwyk, L.C., McGuffin Peter, Darya Gaysina, Craig, Ian W, Farmer, AE, Schosser, A, Gray, J., Elkin, Amanda, Schalkwyk, L., Gray, Joanna, Craig, IW, Schalkwyk Leonard C, Schosser Alexandra, Lisa Jones (98953), Gunasinghe, C, Sarah Cohen-Woods (214940), Pirlo, K., Craig, I.W., Jones Lisa, Alexandra Schosser (214931), Gaysina Darya, Cerisse Gunasinghe (16171376), Schosser, Alexandra, McGuffin, P., Meaburn Emma, Meaburn, E., Amanda Elkin, Leonard C Schalkwyk, Alexandra Schosser, Ania Korszun (214946), Anne E Farmer, Joanna Gray, Lisa Jones, McGuffin, P, Pirlo, Katrina, Elkin Amanda, Katrina Pirlo, Gaysina, Darya, Schosser, A., Elkin, A., Schalkwyk, LC, Korszun, A., Peter McGuffin, Gunasinghe, Cerisse, Amanda Elkin (16049114), Craig Ian W, Sarah Cohen-Woods, Joanna Gray (16171373), Anne E Farmer (10497512), Farmer Anne E, Gaysina, Daria, Ania Korszun, Pirlo, K, Gunasinghe, C., Peter McGuffin (51507), Meaburn, Emma L., Elkin, A, Katrina Pirlo (14918094), Gaysina, D., Cerisse Gunasinghe, Korszun, A, Farmer, A.E., McGuffin, Peter, Korszun, Ania, Jones, Lisa, Leonard C Schalkwyk (8412954), Cohen-Woods, S, McGuffin, Peter W, Meaburn, E, Darya Gaysina (4464832), Schalkwyk, Leonard C, Cohen-Woods, S., Gunasinghe Cerisse, Jones, L., Gunasinghe, Cerisse; id_orcid, Meaburn, Emma   +90 more
core   +1 more source

Evolutionary Computation-Based Memetic Algorithm Against Genetic Algorithm to Improve PCR-RFLP Assay Primers of SNP Genotyping

IEEE Access, 2018
A genetic algorithm (GA) combines the restriction enzyme mining core of single nucleotide polymorphism (SNP) restriction fragment length polymorphism (RFLP) to design polymerase chain reaction (PCR)-RFLP primer pairs for SNP-based genotyping with ...
Yu-Huei Cheng, Ching-Ming Lai, Jiashen Teh, Che-Nan Kuo   +3 more
doaj   +1 more source

Novel approach for deriving genome wide SNP analysis data from archived blood spots [PDF]

, 2012
BACKGROUND: The ability to transport and store DNA at room temperature in low volumes has the advantage of optimising cost, time and storage space.
Walling, Grant A, Fowler Katie E, Fowler, K., Fowler, Katie E., Griffin, Darren K, Griffin, D., Reitter, Chris P, Reitter Chris P, Griffin Darren K, Griffin, Darren K., Reitter, C., Walling, G., Walling Grant A   +12 more
core   +3 more sources

Development of a high-density sub-species-specific targeted SNP assay for Rocky Mountain bighorn sheep (Ovis canadensis canadensis) [PDF]

PeerJ
Due to their abundance and relative ease of genotyping, single nucleotide polymorphisms (SNPs) are a commonly used molecular marker for contemporary population genetic and genomic studies. A high-density and cost-effective way to type SNP loci is Allegro
Samuel Deakin, David W. Coltman
doaj   +2 more sources

An evaluation of genotyping by sequencing (GBS) to map the Breviaristatum-e (ari-e) locus in cultivated barley [PDF]

, 2014
We explored the use of genotyping by sequencing (GBS) on a recombinant inbred line population (GPMx) derived from a cross between the two-rowed barley cultivar 'Golden Promise' (ari-e.GP/Vrs1) and the six-rowed cultivar 'Morex' (Ari-e/vrs1) to map plant ...
Arnis Druka, Jesse Poland, Micha Bayer, Robbie Waugh, Bayer, Micha, Pete E Hedley, Hui Liu, Druka, Arnis, Hackett, Christine A., Luke Ramsay, Ramsay, Luke, Poland, Jesse, Christine A Hackett, Liu, Hui, Hedley, Pete E., Waugh, Robbie; id_orcid, Russell, Joanne R., Joanne R Russell   +17 more
core   +1 more source

SNP Genotyping and ApoE Genotyping V.1 [PDF]

, 2022
This protocol details the steps for DNA extraction from a human blood sample, quality control, and SNP and APOE genotyping. The protocol has been adapted from the PRoBaND SNP Genotyping and ApoE Genotyping Protocol.
Williams, Nigel M., Morris, Huw, Tan, Manuela M.X., Grosset, Donald G.   +3 more
core   +1 more source

Extent of genome-wide linkage disequilibrium in Australian Holstein-Friesian cattle based on a high-density SNP panel [PDF]

, 2008
BACKGROUND: The extent of linkage disequilibrium (LD) within a population determines the number of markers that will be required for successful association mapping and marker-assisted selection.
Andrew R Collins, Zenger, Kyall R., Jeremy F Taylor, Zenger Kyall R, Frank W Nicholas, Cavanagh Julie AL, Taylor, Jeremy F., Barris Wes, Wes Barris, Taylor Jeremy F, Kyall R Zenger, Barris, Wes, Nicholas, Frank W., Julie AL Cavanagh, Schnabel Robert D, Collins, Andrew R., Raadsma Herman W, Raadsma, Herman W., Nicholas Frank W, Herman W Raadsma, Khatkar, Mehar S., Khatkar Mehar S, Collins Andrew R, Nicholas, Mehar S., Cavanagh, Julie A.L., Robert D Schnabel, Mehar S Khatkar, Schnabel, Robert D.   +27 more
core   +1 more source

Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arrays [PDF]

, 2007
High-throughput SNP genotyping platforms use automated genotype calling algorithms to assign genotypes. While these algorithms work efficiently for individual platforms, they are not compatible with other platforms, and have individual biases that result
Smith, Edward M., Olivier, Michael, Olivier, M. (Michael), Littrell, Jack   +3 more
core   +1 more source