Results 31 to 40 of about 219,663 (291)
A machine learning approach for missing persons cases with high genotyping errors
Frontiers in Genetics, 2022 Estimating the relationships between individuals is one of the fundamental challenges in many fields. In particular, relationship.ip estimation could provide valuable information for missing persons cases.
Meng Huang +8 more
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Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12. [PDF]
, 2018 Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather ...
Cheng, HH +7 more
core +1 more source
Diversity, 2020 Single nucleotide polymorphism (SNP) genotyping arrays are powerful tools to measure the level of genetic polymorphism within a population. The coming of next-generation sequencing technologies led to identifying thousands and millions of SNP loci useful
Davide Bianchi +2 more
doaj +1 more source
Comparison of PrASE and Pyrosequencing for SNP Genotyping [PDF]
BMC Genomics, 2006 Abstract Background There is an imperative need for SNP genotyping technologies that are cost-effective per sample with retained high accuracy, throughput and flexibility. We have developed a microarray-based technique and compared it to Pyrosequencing.
Odeberg Jacob +6 more
openaire +3 more sources
Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core +1 more source
Methodological Issues in Multistage Genome-Wide Association Studies [PDF]
, 2009 Because of the high cost of commercial genotyping chip technologies, many investigations have used a two-stage design for genome-wide association studies, using part of the sample for an initial discovery of ``promising'' SNPs at a less stringent ...
Casey, Graham +5 more
core +1 more source
The Invader® assay for SNP genotyping [PDF]
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005 The Invader assay uses a structure-specific flap endonuclease (FEN) to cleave a three-dimensional complex formed by hybridization of allele-specific overlapping oligonucleotides to target DNA containing a single nucleotide polymorphism (SNP) site. Annealing of the oligonucleotide complementary to the SNP allele in the target molecule triggers the ...
openaire +2 more sources
Inference of kinship coefficients from Korean SNP genotyping data [PDF]
BMB Reports, 2013 The determination of relatedness between individuals in afamily is crucial in analysis of common complex diseases. Wepresent a method to infer close inter-familial relationshipsbased on SNP genotyping data and provide the relationshipcoefficient of ...
Seong-Jin Park +5 more
doaj +1 more source
Sequence-based genotyping for marker discovery and co-dominant scoring in germplasm and populations.
PLoS ONE, 2012 Conventional marker-based genotyping platforms are widely available, but not without their limitations. In this context, we developed Sequence-Based Genotyping (SBG), a technology for simultaneous marker discovery and co-dominant scoring, using next ...
Hoa T Truong +10 more
doaj +1 more source
Conflicting Results in SNP Genotype Assessment
BioTechniques, 2007 Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies. Therefore, there is a strong need for high throughput and reliable methodologies to assess the SNP genotypes. Despite an unambiguous result of an SNP analysis,
Hansen, Lise Lotte +3 more
openaire +4 more sources