Results 21 to 30 of about 337,686 (261)

Agrigenomic Diversity Unleashed: Current Single Nucleotide Polymorphism Genotyping Methods for the Agricultural Sciences

open access: yesApplied Biosciences, 2023
Single Nucleotide Polymorphisms (SNPs) are variations that occur at single nucleotides in the genome and are present at an appreciable level in a population.
Roger D. Lawrie, Steven E. Massey
doaj   +1 more source

Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans [PDF]

open access: yes, 2006
The identification of quantitative trait loci (QTLs) of small effect size that underlie complex traits poses a particular challenge for geneticists due to the large sample sizes and large numbers of genetic markers required for genomewide association ...
Plomin, R.   +14 more
core   +1 more source

Comparison of msp genotyping and a 24 SNP molecular assay for differentiating Plasmodium falciparum recrudescence from reinfection

open access: yesMalaria Journal, 2019
Background Current World Health Organization guidelines for conducting anti-malarial drug efficacy clinical trials recommend genotyping Plasmodium falciparum genes msp1 and msp2 to distinguish recrudescence from reinfection.
Joseph Fulakeza   +10 more
doaj   +1 more source

Special features of RAD Sequencing data:implications for genotyping [PDF]

open access: yes, 2012
Restriction site-associated DNA Sequencing (RAD-Seq) is an economical and efficient method for SNP discovery and genotyping. As with other sequencing-by-synthesis methods, RAD-Seq produces stochastic count data and requires sensitive analysis to develop ...
Fuentes-Utrilla, Pablo   +12 more
core   +1 more source

A nanoliter fluidic platform for large-scale single nucleotide polymorphism genotyping

open access: yesBioTechniques, 2009
Discovery, evaluation, and understanding the biological relevance of single nucleotide polymorphisms (SNPs) and their associated phenotypes is relevant to many applications, including human disease diagnostics, pathogen detection, and identification of ...
Douglas G. Roberts   +7 more
doaj   +1 more source

Genotyping by genome reducing and sequencing for outbred animals. [PDF]

open access: yesPLoS ONE, 2013
Next-generation sequencing (NGS) approaches are widely used in genome-wide genetic marker discovery and genotyping. However, current NGS approaches are not easy to apply to general outbred populations (human and some major farm animals) for SNP ...
Qiang Chen   +16 more
doaj   +1 more source

Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages [PDF]

open access: yes, 2012
There is increasing evidence that strain variation in Mycobacterium tuberculosis complex (MTBC) might influence the outcome of tuberculosis infection and disease.
Coscollà Mireia   +54 more
core   +3 more sources

Pooled DNA genotyping on Affymetrix SNP genotyping arrays

open access: yesBMC Genomics, 2006
Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Owen Michael J   +5 more
doaj   +1 more source

The development and characterization of a 60K SNP chip for chicken [PDF]

open access: yes, 2011
Background In livestock species like the chicken, high throughput single nucleotide polymorphism (SNP) genotyping assays are increasingly being used for whole genome association studies and as a tool in breeding (referred to as genomic selection).
Vereijken, Addie   +41 more
core   +2 more sources

Temperature Switch PCR (TSP): Robust assay design for reliable amplification and genotyping of SNPs

open access: yesBMC Genomics, 2009
Background Many research and diagnostic applications rely upon the assay of individual single nucleotide polymorphisms (SNPs). Thus, methods to improve the speed and efficiency for single-marker SNP genotyping are highly desirable.
Mather Diane E   +2 more
doaj   +1 more source

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