Results 21 to 30 of about 129,104 (260)

Evolutionary Computation-Based Memetic Algorithm Against Genetic Algorithm to Improve PCR-RFLP Assay Primers of SNP Genotyping

open access: yesIEEE Access, 2018
A genetic algorithm (GA) combines the restriction enzyme mining core of single nucleotide polymorphism (SNP) restriction fragment length polymorphism (RFLP) to design polymerase chain reaction (PCR)-RFLP primer pairs for SNP-based genotyping with ...
Yu-Huei Cheng   +3 more
doaj   +1 more source

Development of a high-density sub-species-specific targeted SNP assay for Rocky Mountain bighorn sheep (Ovis canadensis canadensis) [PDF]

open access: yesPeerJ
Due to their abundance and relative ease of genotyping, single nucleotide polymorphisms (SNPs) are a commonly used molecular marker for contemporary population genetic and genomic studies. A high-density and cost-effective way to type SNP loci is Allegro
Samuel Deakin, David W. Coltman
doaj   +2 more sources

SNP Genotyping and ApoE Genotyping v1

open access: yes, 2021
This protocol details the steps for DNA extraction from a human blood sample, quality control, and SNP and APOE genotyping. The protocol has been adapted from the PRoBaND SNP Genotyping and ApoE Genotyping Protocol. The overall protocol for PRoBaND /Tracking Parkinson’s is published: Malek, N., Swallow, D. M. A., Grosset, K. A., Lawton, M.
Huw Morris   +3 more
openaire   +1 more source

A machine learning approach for missing persons cases with high genotyping errors

open access: yesFrontiers in Genetics, 2022
Estimating the relationships between individuals is one of the fundamental challenges in many fields. In particular, relationship.ip estimation could provide valuable information for missing persons cases.
Meng Huang   +8 more
doaj   +1 more source

Genetic Diversity and Population Structure in a Vitis spp. Core Collection Investigated by SNP Markers

open access: yesDiversity, 2020
Single nucleotide polymorphism (SNP) genotyping arrays are powerful tools to measure the level of genetic polymorphism within a population. The coming of next-generation sequencing technologies led to identifying thousands and millions of SNP loci useful
Davide Bianchi   +2 more
doaj   +1 more source

Sequence-based genotyping for marker discovery and co-dominant scoring in germplasm and populations.

open access: yesPLoS ONE, 2012
Conventional marker-based genotyping platforms are widely available, but not without their limitations. In this context, we developed Sequence-Based Genotyping (SBG), a technology for simultaneous marker discovery and co-dominant scoring, using next ...
Hoa T Truong   +10 more
doaj   +1 more source

Inference of kinship coefficients from Korean SNP genotyping data [PDF]

open access: yesBMB Reports, 2013
The determination of relatedness between individuals in afamily is crucial in analysis of common complex diseases. Wepresent a method to infer close inter-familial relationshipsbased on SNP genotyping data and provide the relationshipcoefficient of ...
Seong-Jin Park   +5 more
doaj   +1 more source

Reference-free SNP calling: improved accuracy by preventing incorrect calls from repetitive genomic regions

open access: yesBiology Direct, 2012
Background Single nucleotide polymorphisms (SNPs) are the most abundant type of genetic variation in eukaryotic genomes and have recently become the marker of choice in a wide variety of ecological and evolutionary studies.
Dou Jinzhuang   +8 more
doaj   +1 more source

The Invader® assay for SNP genotyping [PDF]

open access: yesMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005
The Invader assay uses a structure-specific flap endonuclease (FEN) to cleave a three-dimensional complex formed by hybridization of allele-specific overlapping oligonucleotides to target DNA containing a single nucleotide polymorphism (SNP) site. Annealing of the oligonucleotide complementary to the SNP allele in the target molecule triggers the ...
openaire   +2 more sources

Comparison of PrASE and Pyrosequencing for SNP Genotyping [PDF]

open access: yesBMC Genomics, 2006
Abstract Background There is an imperative need for SNP genotyping technologies that are cost-effective per sample with retained high accuracy, throughput and flexibility. We have developed a microarray-based technique and compared it to Pyrosequencing.
Odeberg Jacob   +6 more
openaire   +3 more sources

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