Results 191 to 200 of about 219,632 (346)

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Updated resource of 180K soybean SNP genotyping array based on the T2T reference genome. [PDF]

PLoS One
Hwang JH, Lee S, Lee JS, Kim KD.
europepmc   +1 more source

SNP Genotyping Characterizes the Genome Composition of the New Baisary Fat-Tailed Sheep Breed. [PDF]

Animals (Basel), 2022
Zhumadillayev N, Dossybayev K, Khamzina A, Kapasuly T, Khamzina Z, Tlevlesov N.   +5 more
europepmc   +1 more source

The Impact of Genotoxicity in Coke Oven Workers: Systematic Review With Meta‐Analysis

Journal of Applied Toxicology, EarlyView.
ABSTRACT This systematic review (SR) with meta‐analysis investigates the genotoxicity potential of coke oven workers (COWs) exposed to polycyclic aromatic hydrocarbons (PAHs) through a comprehensive analysis of studies retrieved from PubMed, SCOPUS, and Web of Science.
Thiago Guedes Pinto, Vinícius Fialho do Nascimento, Giovanna Abreu Holanda Guerra, Wilton Mitsunari Takeshita, Raquel Alves Sales, Andrea Cristina de Moraes Malinverni, Luciana Lopes Guimaraes, Daniel Araki Ribeiro   +7 more
wiley   +1 more source

Comparative assessment of SNP genotyping assays for challenging forensic samples utilizing ancient DNA methods. [PDF]

Genome Biol
Staadig A, Krzewińska M, Sidstedt M, Kling D, Fagerholm SA, Ansell R, Götherström A, Tillmar A.   +7 more
europepmc   +1 more source

Development of a Next Generation SNP Genotyping Array for Wheat

, 2023
Burridge AJ, Winfield M, Przewieslik-Allen A, Edwards KJ, Siddique I, Barral-Arca R, Griffiths S, Cheng S, Huang Z, Feng C, Dreisigacker S, Bentley AR, Brown-Guedira G, Barker GL.   +13 more
europepmc   +1 more source

Filaggrin genotyping using Taqman SNP genotyping assays v1

The FLG gene encodes the filaggrin protein which is essential for epidermal barrier formation and hydration. Mutations in the filaggrin gene are associated with a broad range of skin and allergic diseases. This protocol is used to genotype four mutations (R501X, 2282del4, R2447X and S3247X) within the FLG gene.
Angie Fawkes, Katarzyna Hafezi, Lee Murphy   +2 more
openaire   +1 more source

An Integrated Genotyping Strategy for α/β‐Thalassemia: Based on the Analysis of the Coding Sequences and Expression Levels of HBA2, HBA1, and HBB in Peripheral Blood mRNA

Journal of Clinical Laboratory Analysis, EarlyView.
We have developed an integrated mRNA‐based strategy for thalassemia genotyping. Its characteristics included using only three Sanger sequencing reactions to analyze the full‐length coding sequence of HBA2, HBA1 and HBB, and employing a new multiple quantitative fluorescence PCR to simply assess and present the impact of common mutations on the ...
Hongjian Chen, Qi Yao, Mianai Fu
wiley   +1 more source

Development and validation of a 70K SNP genotyping array for Atlantic halibut (Hippoglossus hippoglossus). [PDF]

BMC Genomics
Sinani VK, Wilson RC, Nome T, Acharya U, Kommisrud E, Wetten M, Kent MP.   +6 more
europepmc   +1 more source

Role of EFNA1 SNP (rs12904) in Tumorigenesis and Metastasis of Colorectal Cancer: A Bioinformatic Analysis and HRM SNP Genotyping Verification. [PDF]

Asian Pac J Cancer Prev, 2022
Salem E, Keshvari A, Mahdavinezhad A, Soltanian AR, Saidijam M, Afshar S.   +5 more
europepmc   +1 more source