Results 271 to 280 of about 120,949 (314)

Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose‐limiting complications and compromised event‐free survival. Procedure This study conducted a genome‐wide association study (GWAS) in a discovery cohort of
Spencer J. Anderson   +10 more
wiley   +1 more source

A low-density SNP genotyping panel for the accurate prediction of cattle breeds. [PDF]

open access: yesJ Anim Sci, 2020
Reverter A   +9 more
europepmc   +1 more source

Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings

open access: yesPediatric Discovery, EarlyView.
Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong   +13 more
wiley   +1 more source

Forgetting cane grasses: Switching temporal focus to reveal mosaics of Saccharum diversity

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Sugarcane (Saccharum cvs.) is one of the most important cash crops globally. Related varieties and species of cane grasses of the genus Saccharum are also important subsistence crops in the Indo‐Pacific region. Despite the significance of these crops globally and recent advances in genetic characterisation, the histories and geographies of ...
Tim Denham
wiley   +1 more source

Genomic dissection of productivity, lodging, and morpho‐physiological traits in Eragrostis tef under contrasting water availabilities

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Underutilized species (also known as orphan crops) present opportunities to increase crop diversity and food security. Such crops lack modern genetic tools and knowledge to facilitate efficient modern breeding approaches. A wide collection of tef (Eragrostis tef (Zucc.) Trotter) genotypes was used to identify genomic regions associated with ...
Muluken Demelie Alemu   +10 more
wiley   +1 more source

Detecting SARS-CoV-2 variants with SNP genotyping

open access: yes, 2020
Harper H   +11 more
europepmc   +1 more source

The potential of seedbank digital information in plant conservation

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Seedbanks are vital for biodiversity conservation, but their potential remains underutilised due to a limited understanding of the intraspecific genetic diversity they hold. By leveraging digitised data associated with seedbank collections, such as sampling locations, number of maternal plants and seed traits, we can attempt the estimation of genetic ...
Roberta Gargiulo   +23 more
wiley   +1 more source

Different nontarget‐site mechanisms underlie resistance to dicamba and 2,4‐D in an Amaranthus tuberculatus population

open access: yesPest Management Science, EarlyView.
Weak phenotypic and genetic associations between resistance to dicamba and 2,4‐D suggest that different nontarget‐site mechanisms contribute to these traits in an Amaranthus tuberculatus population from Illinois. Abstract BACKGROUND Amaranthus tuberculatus (Moq.) Sauer (waterhemp) has emerged as one of several weed species that is resistant to ...
Isabel Schlegel Werle   +5 more
wiley   +1 more source

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