Results 81 to 90 of about 201,829 (351)

A High-Density Linkage Map of the Ancestral Diploid Strawberry, Fragaria iinumae, Constructed with Single Nucleotide Polymorphism Markers from the IStraw90 Array and Genotyping by Sequencing [PDF]

, 2016
Fragaria iinumae Makino is recognized as an ancestor of the octoploid strawberry species, which includes the cultivated strawberry, Fragaria ×ananassa Duchesne ex Rozier.
Abebe-Akele, Feseha, Bassil, Nahla V., Davis, Thomas M., Folta, Kevin M., Hancock, James F., Mahoney, Lise L., Sargent, Daniel J., Ward, Judson A., Wood, David J.   +8 more
core   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

InDelGT: An integrated pipeline for extracting indel genotypes for genetic mapping in a hybrid population using next‐generation sequencing data

Applications in Plant Sciences, Volume 10, Issue 6, November-December 2022., 2022
Abstract Premise Although several software packages are available for genotyping insertion/deletion (indel) polymorphisms in genomes using next‐generation sequencing data, simultaneously calling indel genotypes across many individuals for use in genetic mapping remains challenging. Methods and Results We present an integrated pipeline, InDelGT, for the
Zhiliang Pan, Jinpeng Zhang, Shengjun Bai, Zhiting Li, Chunfa Tong   +4 more
wiley   +1 more source

The Development of Quality Control Genotyping Approaches: A Case Study Using Elite Maize Lines. [PDF]

PLoS ONE, 2016
Quality control (QC) of germplasm identity and purity is a critical component of breeding and conservation activities. SNP genotyping technologies and increased availability of markers provide the opportunity to employ genotyping as a low-cost and robust
Jiafa Chen, Cristian Zavala, Noemi Ortega, Cesar Petroli, Jorge Franco, Juan Burgueño, Denise E Costich, Sarah J Hearne   +7 more
doaj   +1 more source

Characterization of duplicate gene evolution in the recent natural allopolyploid Tragopogon miscellus by next-generation sequencing and Sequenom iPLEX MassARRAY genotyping [PDF]

, 2010
The definitive version is available at www.blackwell-synergy ...
Adams, Adams, Adams, Ainouche, Barbazuk, Bottley, Buggs, Buggs, Buggs, Cannon, Chaisson, Chaudhary, Chen, Chen, Cheung, Cheung, Cook, Cook, Dong, Doyle, Dunstan, Ellegren, Elmer, Emrich, Eveland, Feldman, Ferguson, Flagel, Flagel, Gabriel, Gaeta, Goetz, Guo, Gut, Harr, Hegarty, Hegarty, Hillier, Holt, Hudson, Johnson, Joly, Judd, Kashkush, Kihara, Kim, Kim, Kovarik, Kwok, Levy, Lim, Lim, Liu, Lynch, Margulies, Marth, Matyasek, Mavrodiev, Novaes, Novak, Ownbey, Pavy, Petit, Quackenbush, Renaut, Sadava, Slate, Soltis, Soltis, Soltis, Soltis, Soltis, Song, Stebbins, Stupar, Swanson-Wagner, Tate, Tate, Tate, Udall, Van Bers, Van Tassell, Vera, Wang, Wang, Whittall, Wolf   +86 more
core   +1 more source

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage. [PDF]

, 2019
One fundamental but understudied mechanism of gene regulation in disease is allele-specific expression (ASE), the preferential expression of one allele.
A Chess, A de la Chapelle, A Gimelbrant, A Hogart, A McKenna, A Mortazavi, AA Adegbola, AL Oberg, AM Veerappa, B DeVeale, B Howie, B Langmead, B Tycko, C Fuchsberger, C Gicquel, C Gregg, C Lee, CA de Leeuw, CCY Wong, Changhoon Lee, Cross-Disorder Group of the Psychiatric Genomics Consortium., D Kim, Daniel H. Geschwind, DH Geschwind, E Ben-David, E Eden, E Eden, E Gardiner, EH Cook Jr., Eleazar Eskin, EM Quinn, Eun Yong Kang, EY Kang, F Supek, GT Consortium, GV Kryukov, H Li, HA Scoles, I Iossifov, I Voineagu, J Cavaille, J Cavaille, J Grove, JC Darnell, JF Degner, JK Pickrell, KR Kukurba, M Elsabbagh, M Meguro-Horike, Michael J. Gandal, N Mukherjee, NN Parikshak, NN Parikshak, PH Sudmant, PS Bazeley, R Karlic, S Anders, S Kehr, S Kishore, S Nardone, S Purcell, Schizophrenia Working Group of the Psychiatric Genomics Consortium., SE Castel, SJ Sanders, SM Weyn-Vanhentenryck, T Hulsen, V Savova, Y Zhang, YE Wu   +68 more
core   +1 more source

A Joint Use of Pooling And Imputation For Genotyping SNPs

BMC Bioinformatics, 2021
Abstract Background: Despite continuing technological advances, the cost for large-scale genotyping of a high number of samples can be prohibitive. The purpose of this study is to design a cost-saving strategy for SNP genotyping. We suggest making use of pooling, a group testing technique, to drop the amount of SNP arrays needed.
Clouard, Camille, Ausmees, Kristiina, Nettelblad, Carl   +2 more
openaire   +4 more sources

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Single nucleotide polymorphisms in the CDH18 gene affect growth traits in Hu sheep

Animal Research and One Health, EarlyView., 2023
Abstract Growth traits are critical economic traits in sheep. Genetic polymorphism has a great influence on the improvement of sheep traits. The aim of this study was to analyze the effect of cadherin 18 (CDH18) gene polymorphisms on growth traits in Hu sheep.
Tianyi Liu, Yazhen Bi, Jingjing Bao, Mingyu Shang, Wenping Hu, Li Zhang   +5 more
wiley   +1 more source