Results 91 to 100 of about 526,264 (266)
Romanian Journal of Internal MedicineBackground: Aldosterone synthase (CYP11B2) is crucial for aldosterone production, and variations in its gene may influence type 2 diabetes mellitus (T2DM) development. This study explores the link between two single nucleotide polymorphisms (SNPs) in the
Nouhi Youssef +4 more
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Advanced Healthcare Materials, EarlyView.This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen +13 more
wiley +1 more source
Advanced Science, EarlyView.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Prioritization of rs187728237 and rs80320514 as miRNA-related Variants of Human AEG-1 Gene
Medical Laboratory Journal, 2018 Background and objectives: 3chr('39') untranslated region (3chr('39')UTR) single nucleotide polymorphisms (SNPs) represent genetic variations that may potentially affect binding of miRNA to coding genes, potentially leading to complex disorders.
Semira Kheiri +3 more
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Advanced Science, EarlyView.This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
Evaluation of the Role of Two SNPs in MTHFR Gene Polymorphisms (rs1801133) 677 C>T and (rs 1801131) 1298A>C with Homocysteine Level in Iraqi Patients with Chronic Kidney Disease [PDF]
Modern MedicineObjectives: Objectives: The current study was designed to evaluate the role of MTHFR gene (rs1801133 and rs1801131) polymorphisms and investigate the serum Homocysteine level in Iraqi patients with CKD.
Saife AL-AHMER +2 more
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PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites
Advanced Science, EarlyView.This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang +13 more
wiley +1 more source
Association of the ENPP1/ENTPD1 Polymorphisms in Hemodialysis Patients
International Journal of General Medicine, 2021 Xi Zhang,1 Ziming Wan,1 Si Cheng,2 Hua Gan1 1Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical ...
Zhang X, Wan Z, Cheng S, Gan H
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Relationship of FTO gene variations with NAFLD risk in Chinese men
Open Life Sciences, 2020 Fat mass and obesity-associated (FTO) gene is an obesity susceptibility gene and its relationship with the nonalcoholic fatty liver disease (NAFLD) remains unclear.
Chen Xuefen +5 more
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G3: Genes, Genomes, Genetics, 2020 Fusarium verticillioides, which causes ear, kernel and stem rots, has been reported as the most prevalent species on maize worldwide. Kernel infection by F. verticillioides results in reduced seed yield and quality as well as fumonisin contamination, and
Lorenzo Stagnati +7 more
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