Results 11 to 20 of about 524,252 (269)

Multiple Testing for SNP-SNP Interactions [PDF]

Statistical Applications in Genetics and Molecular Biology, 2007
Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators.
Anne-Laure, Boulesteix, Carolin, Strobl, Stefan, Weidinger, H-Erich, Wichmann, Stefan, Wagenpfeil   +4 more
openaire   +2 more sources

SNP-Flankplus: SNP ID-centric retrieval for SNP flanking sequences [PDF]

Bioinformation, 2008
The flanking sequences provided by dbSNP of NCBI are usually short and fixed length without further extension, thus making the design of appropriate PCR primers difficult. Here, we introduce a tool named "SNP-Flankplus" to provide a web environment for retrieval of SNP flanking sequences from both the dbSNP and the nucleotide databases of NCBI. Two SNP
Cheng-Hong, Yang, Yu-Huei, Cheng, Li-Yeh, Chuang, Hsueh-Wei, Chang   +3 more
openaire   +2 more sources

SNP-VISTA: An interactive SNP visualization tool [PDF]

BMC Bioinformatics, 2005
Abstract Background Recent advances in sequencing technologies promise to provide a better understanding of the genetics of human disease as well as the evolution of microbial populations. Single Nucleotide Polymorphisms (SNPs) are established genetic markers that aid in the identification of loci affecting quantitative ...
Shah, Nameeta, Teplitsky, Michael V., Minovitsky, Simon, Pennacchio, Len A., Hugenholtz, Philip, Hamann, Bernd, Dubchak, Inna L.   +6 more
openaire   +5 more sources

SNP-SNP interactions in breast cancer susceptibility [PDF]

BMC Cancer, 2006
AbstractBackgroundBreast cancer predisposition genes identified to date (e.g., BRCA1 and BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer risks associated with individual commonly occurring single nucleotide polymorphisms (SNPs) are incremental.
Onay, Venüs Ü, Briollais, Laurent, Knight, Julia A, Shi, Ellen, Wang, Yuanyuan, Wells, Sean, Li, Hong, Rajendram, Isaac, Andrulis, Irene L, Ozcelik, Hilmi   +9 more
openaire   +4 more sources

SNP-PHAGE – High throughput SNP discovery pipeline [PDF]

BMC Bioinformatics, 2006
AbstractBackgroundSingle nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. As a result of their abundance and the availability of high throughput analysis technologies SNP markers have begun to replace other traditional markers such as ...
Matukumalli, Lakshmi K., Grefenstette, John J., Hyten, David L., Choi, Ik-Young, Cregan, Perry B., Van Tassell, Curt P.   +5 more
openaire   +3 more sources

Low-density genotype panel for both parentage verification and discovery in a multi-breed sheep population [PDF]

, 2019
peer-reviewedThe generally low usage of artificial insemination and single-sire mating in sheep, compounded by mob lambing (and lambing outdoors), implies that parentage assignment in sheep is challenging.
Berry, Donagh, McDermott, K., McHugh, Noirin, O’Brien, A.C., Wall, E.   +4 more
core   +1 more source

Evaluation of the Role of Two SNPs in MTHFR Gene Polymorphisms (rs1801133) 677 C>T and (rs 1801131) 1298A>C with Homocysteine Level in Iraqi Patients with Chronic Kidney Disease [PDF]

Modern Medicine
Objectives: Objectives: The current study was designed to evaluate the role of MTHFR gene (rs1801133 and rs1801131) polymorphisms and investigate the serum Homocysteine level in Iraqi patients with CKD.
Saife AL-AHMER, Basima AL-SAADI, Ali AL SAEDI   +2 more
doaj   +1 more source

Joint analysis of SNP and gene expression data in genetic association studies of complex diseases [PDF]

, 2014
Genetic association studies have been a popular approach for assessing the association between common Single Nucleotide Polymorphisms (SNPs) and complex diseases.
Huang, Yen-Tsung, Lin, Xihong, VanderWeele, Tyler J.   +2 more
core   +1 more source

Relationship of FTO gene variations with NAFLD risk in Chinese men

Open Life Sciences, 2020
Fat mass and obesity-associated (FTO) gene is an obesity susceptibility gene and its relationship with the nonalcoholic fatty liver disease (NAFLD) remains unclear.
Chen Xuefen, Gao Yong, Yang Xiaobo, Zhang Haiying, Mo Zengnan, Tan Aihua   +5 more
doaj   +1 more source

A Genome-Wide Association Study To Understand the Effect of Fusarium verticillioides Infection on Seedlings of a Maize Diversity Panel

G3: Genes, Genomes, Genetics, 2020
Fusarium verticillioides, which causes ear, kernel and stem rots, has been reported as the most prevalent species on maize worldwide. Kernel infection by F. verticillioides results in reduced seed yield and quality as well as fumonisin contamination, and
Lorenzo Stagnati, Vahid Rahjoo, Luis F. Samayoa, James B. Holland, Virginia M. G. Borrelli, Matteo Busconi, Alessandra Lanubile, Adriano Marocco   +7 more
doaj   +1 more source