Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Background: HIV infection is a new social phenomenon that affects almost all aspects of a person’s mental, physical, social and economic health in life.
Reza Mirzaei +3 more
doaj
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Early Adolescents and Exposure to Risks Online: What Is the Role of Parental Mediation Styles?
Studies indicate that early adolescents are exposed to several online risks. Furthermore, early adolescents with Special Educational Needs (SENs) often experience emotional, social, or family difficulties, which increase their vulnerability to online ...
Clara Cavallini +2 more
doaj +1 more source
An assessment of counseling needs among international graduate students: implications for university students’ programmes and services [PDF]
Interest in going abroad for studies is getting higher in Indonesia. But foreign students will find it even more problematic, because they face both the normal adjustment problems of studying in university plus adjustment problems of adapting to a ...
Rahaju, Soerjantini
core
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Philippines: External Shocks, Adjustment Policies and Impact on Selected Development Concerns, 1973-1985 [PDF]
With the objective of designing and implementing more effective policies and programs in the light of external shocks, this paper assesses the impact of economic crisis and adjustment policies on basic economic and social concerns particularly on ...
Bernal, Norma B. +3 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The effectiveness of teaching emotion-based processing strategies on academic stress, social adjustment and psychological distress of high school male students [PDF]
Background: Studies have shown that the experience of emotions in educational environments affects academic stress, social adjustment and psychological distress. The basic experiential processing method under the title of emotion-oriented processes leads
kianoosh beyranvand +3 more
doaj

