Results 91 to 100 of about 1,787,877 (302)
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Economic, social and cultural rights have borne the brunt of the recent economic crisis and the austerity measures adopted to counter it. Due to their gradual implementation and the need of positive measures to implement them, they were the first to be ...
Vasiliki Saranti
doaj
Introduction: Fulfillment of economic, social and cultural rights is a reflection of guaranteeing human rights. However, the economic, social and cultural rights of every citizen must be supported by their status as a citizen.
Lusi K. F. R. Gerungan +2 more
doaj +1 more source
The relationship between foreign development assistance and human rights peerformance : a case study of the United States of America, Canada, The Netherlands and Indonesia : a research project presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Development Studies at Massey University [PDF]
This dissertation examines the degree to which donor countries have attempted to suspend or discontinue foreign aid to the recipients on human rights ground.
Costa Babo Soares, Dionisio da
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Are agri-business companies responsible for land grabbing in Central Africa? [PDF]
Land grabbing usually refers to the controversial acquisition of a piece of land. As such it is a social concept. It deals with social and cultural use of and access to land, and with land tenure, including customary and legal rights.
Aboubakar Hayatou, Iyabano +7 more
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We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Intellectual Property and Indigenous Culture [PDF]
The extent to which cultural activities can generate social and economic benefits for Indigenous communities, and the way in which those benefits are shared within communities depends largely on the way in which the system of intellectual property rights
John Quiggin, Robynne Quiggin
core
Digging deep the oil world: corporate liability and environmental justice strategies [PDF]
The impacts provoked by the expanding oil industry encompass environmental destruction, health impacts and violations of human rights. The increasing contamination jeopardizes safe conditions of life and destroys means of livelihood of vulnerable ...
Certomà, Chiara +4 more
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

