Results 81 to 90 of about 1,787,877 (302)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Cultural rights as an integral part of the human rights system
RUDN Journal of Law, 2011 This article examines the place of cultural rights in the system of fundamental rights and freedoms. We consider the interpretation of cultural rights in various international instruments and in the General comments of the Committee on Economic, Social ...
Е А Kukin
doaj
Right to Health in International Human Rights Law [PDF]
حقوق بشر, 2007 Right to health is among the basic and fundamental human rights recognized in international human rights law. This notwithstanding, the concept and content of the right and the corresponding State obligations are yet to be outlined.
Mohammad Habibi Mojandeh
doaj
Economics for Human Rights [PDF]
The Subprime Crash that started capitalism’s latest crisis was mainly a proxy for an inexistent housing policy which would benefit many impoverished middle class families.
Manuel Couret Branco
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Homa Publica, 2019 The work in question therefore aims to analyze the extraterritorial obligations of International Covenant of Economic, Social and Cultural Rights (ICESCR) Contracting Parties in the context of development cooperation operations that could jeopardize the ...
Dimitris Liakopoulos
doaj
FREEDOM OF EXPRESSION AS A PREMISE FOR THE DIVERSITY OF CULTURAL EXPRESSIONS
Revista Eletrônica do Curso de Direito da UFSM, 2019 The right to participate and benefit from culture is a human right, its scope is defined in the international arena through the International Covenant on Economic, Social and Cultural Rights that in article 15 establishes various cultural rights such as:
Luis Gerardo Rodriguez Lozano
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The judicial and legal framework of culture. Cultural Rights
Periférica, 2018 After the recognition, firstly, of civil and political rights, then of economic, social and cultural rights, there was a need to proclaim and recognise, in both international treaties and in more recent constitutional texts, the so-called third ...
Juana Escudero Méndez
doaj
Laws, 2016 In light of the recent adoption of the Optional Protocol to the International Covenant on Economic, Social and Cultural Rights (OP-ICESCR) and the Optional Protocol to the Convention on the Rights of Persons with Disabilities (OP-CRPD), there is a ...
Andrea Broderick
doaj +1 more source