Results 91 to 100 of about 20,716,741 (337)
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
Respecifying social change: the obsolescence of practices and the transience of technology. [PDF]
Mlynář J, Arminen I.
europepmc +1 more source
Social Policy and Social Change in Western India, 1817-1830. [PDF]
Stanley Wolpert, Kenneth Ballhatchet
openalex +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li+3 more
wiley +1 more source
MAN IN SPACE: A TOOL AND PROGRAM FOR THE STUDY OF SOCIAL CHANGE [PDF]
Donald N. Michael
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In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker+8 more
wiley +1 more source
Research note. Valuation Mishaps and the Choreography of Repair
This research note proposes that it is instructive to ask what happens when evaluative practices go wrong. It shows how a close study of mistakes and mishaps in evaluation - both in the process of their disclosure and subsequent management - provides ...
Claes-Fredrik Helgesson, Steve Woolgar
doaj +1 more source
CHANGING IDEALS IN EDUCATION SOCIAL CHANGES IN THE COLLEGES SINCE THE CIVIL WAR [PDF]
Charles F. Thwing
openalex +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász+6 more
wiley +1 more source