Results 111 to 120 of about 6,972,461 (360)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Respecifying social change: the obsolescence of practices and the transience of technology. [PDF]
Front Sociol, 2023 Mlynář J, Arminen I.
europepmc +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Changes in air quality during and after large-scale social restriction periods in Jakarta city, Indonesia [PDF]
, 2022 Muhammad Rendana +2 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Social Change: The Sexual Revolution [PDF]
In 1900 only six percent of unwed females engaged in premarital sex. Now, three quarters do. The sexual revolution is studied here using an equilibrium matching model, where the costs of premarital sex fall over time due to technological improvement in ...
Jeremy Greenwood, Nezih Guner
core
Journal of Integrative Environmental Sciences, 2019 The paper covers the public debate on BECCS (bioenergy with carbon capture and storage) between 2008 and 2018. Through a qualitative analysis of around 800 feature articles, editorials, and opinion pieces published in English, German, Swedish, Danish ...
Simon Haikola +2 more
doaj +1 more source
Distance Education in Social Work During the COVID-19 Pandemic: Changes and Challenges [PDF]
, 2021 Suzanne Lischer +4 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source