Results 51 to 60 of about 1,384,639 (301)

Growing decision-making: the role of theory of mind, empathy, and personality traits in school-age children

Frontiers in Psychology
Children’s decision-making is a socio-cognitive skill embedded within a broader system that promotes understanding of others and effective management of interpersonal contexts, making it closely linked to Theory of Mind (ToM) and empathy.
Elisabetta Lombardi, Cinzia Di Dio, Ilaria Castelli, Davide Massaro, Antonella Marchetti, Annalisa Valle   +5 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The role of social and emotional competence on risk behaviors in adolescence [PDF]

, 2012
The purpose of this study was to investigate the relation between social and emotional competence and substance use in adolescence, including tobacco, alcohol and illicit drugs.
Alves Diniz, Jose, Ferreira, Mafalda, Gaspar Matos, Margarida, Ramiro, Lucia, Simoes, Celeste, Social Adventure Team   +5 more
core  

Early Social-Emotional Functioning and Public Health: The Relationship Between Kindergarten Social Competence and Future Wellness [PDF]

, 2015
A new 20-year study shows a link between children's social skills in kindergarten and their well-being in early adulthood.Researchers from Pennsylvania State and Duke Universities analyzed what happened to nearly 800 kindergarteners from four locations ...
Damon E. Jones, Mark Greenberg, Max Crowley   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Curiosity and its role in cross-cultural knowledge creation [PDF]

, 2016
This paper explores the role of curiosity in promoting cross-cultural knowledge creation and competence development. It is based on a study with four international higher educational institutions, all of which offer management and business education ...
Mikhaylov, Natalie S.
core   +5 more sources

Post-simulation debriefing as a stepping stone to self-reflection and increased awareness — a qualitative study

Advances in Simulation
Background The voice of the students should be engaged in simulation curriculum development. Involving the students in the development of debriefing strategies might result in a deeper understanding of learning. However, few studies have investigated the
Sissel Eikeland Husebø, Inger Åse Reierson, Anette Hansen, Hilde Solli   +3 more
doaj   +1 more source

A rasch-based validity study of the HSCL-25

Journal of Affective Disorders Reports, 2021
Background: The Hopkins Symptom Checklist-25 (HSCL-25) is a commonly used questionnaire to assess anxiety and depression in trauma-affected refugees. Despite numerous studies evaluating criterion validity and reliability, few studies have assessed the ...
Erik Vindbjerg, Erik Lykke Mortensen, Guido Makransky, Tine Nielsen, Jessica Carlsson   +4 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Social Competence: Why Is This Important? [PDF]

, 2017
Dr.
Oliver, Brandie M.
core   +1 more source