Results 31 to 40 of about 11,718,333 (235)

“Storia naturale”, “preistoria sociale” e studio del linguaggio nell’approccio costruzionista ai problemi sociali

open access: yesSocietàMutamentoPolitica: Rivista Italiana di Sociologia, 2018
Note critiche attraverso i testi di Donileen R. Loseke e Joel Best (a cura di), special issues on Constructionist Futures: New Directions in Social Problems Theory, in «Qualitative Sociology Review», vol. XI, n.
Enrico Caniglia
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Critical-discursive social constructionism: what is the standpoint of social constructionism research? [PDF]

open access: yes, 2021
An overview of critical-discursive Social Constructionism is presented, showing its historical development and its critique of any methodological approaches that do not take into consideration the social-historical reality.
Martínez Richard, Janicce
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Social constructionism in vocational psychology and career development

open access: yes, 2012
This is the fourth book published in the Sense Publishers Career Development Series which began in 2006. The current work addresses the scholarship of social constructionism and its place in disciplinary and professional endeavours of vocational ...
Schultheiss, Donna E., McIlveen, Peter
core   +1 more source

Theories of social constructivism in Anglophone historical epistemology in 2000-2015

open access: yesSHS Web of Conferences, 2016
Social constructionism can be seen as a source of the postmodern movement, and has been influential in the field of cultural studies. The article is devoted to the analysis of the influence of social constructionism in modern Anglophone historiography ...
Ageeva Vera
doaj   +1 more source

A social constructionist approach to resilience for lesbian, gay, bisexual, transgender, intersex, queer and/or questioning academics and students in South African universities

open access: yesTransformation in Higher Education, 2018
This article provides a theoretical contemplation on how reciprocation of an assimilationist, liberationist and/or transgressive approach by lesbian, gay, bisexual, transgender, intersex, queer and/or questioning (LGBTIQ+) individuals on university ...
Jacques Rothmann
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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