Results 51 to 60 of about 7,525 (279)

Theories of social constructivism in Anglophone historical epistemology in 2000-2015

SHS Web of Conferences, 2016
Social constructionism can be seen as a source of the postmodern movement, and has been influential in the field of cultural studies. The article is devoted to the analysis of the influence of social constructionism in modern Anglophone historiography ...
Ageeva Vera
doaj   +1 more source

A social constructionist approach to resilience for lesbian, gay, bisexual, transgender, intersex, queer and/or questioning academics and students in South African universities

Transformation in Higher Education, 2018
This article provides a theoretical contemplation on how reciprocation of an assimilationist, liberationist and/or transgressive approach by lesbian, gay, bisexual, transgender, intersex, queer and/or questioning (LGBTIQ+) individuals on university ...
Jacques Rothmann
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Telling tales of relations: Appreciating relational constructionism

, 2011
The terms social constructionism and (social) constructivism are employed in the context of different problematics and different philosophical assumptions. This article presents ‘relational constructionism’ as a social science perspective.
Dian Marie Hosking, Hosking, D.M., LS Management van Cultuur en Zingeving, UU LEG Research USG Public Matters Managing Social Issues   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Psychology, science and constructionisms: making sense of self / Psicologia, ciência e construcionismos: dando sentido ao self

Psicologia: Reflexão e Crítica, 2004
Social constructionism has been proposed as a set of answers for the scientific paradigmatic crisis of last decades. The complexity and richness of its statements make difficult a unitary and consensual description of what is social constructionism among
Emerson F. Rasera, Carla Guanaes, Marisa Japur   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Společnost jako sociální konstrukce a text

Teorie vědy, 2009
Society as Social Construction and Text The moderate interpretation of the Thomas’ Theorem suggests little more than a failure at the assessment of objective situation. Its radical interpretation allows thinking the existence of new social reality.
Miloslav Petrusek
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Reflective Equilibrium and Normative Reconstruction: Recasting the Phenomenological Deficit of Critical Theory

Ethic@: an International Journal for Moral Philosophy, 2014
In this paper, which reflects an ongoing interdisciplinary research in Cognitive and Social Sciences, I recast the normative claims of a political constructivism in reflective equilibrium (Rawls) and of a formal, pragmatic reconstruction (Habermas) as ...
Nythamar H. F. de Oliveira
doaj   +1 more source