Results 61 to 70 of about 11,718,333 (235)

Social Constructionist Psychology and its Application. Possibilities for a Reorientation

open access: yesForum: Qualitative Social Research, 2008
Social constructionism currently is understood as a metatheoretical alternative to positivism. It serves many social and cultural scientists as a point of reference.
Johannes von Tiling
doaj  

Telling tales of relations: Appreciating relational constructionism [PDF]

open access: yes, 2011
The terms social constructionism and (social) constructivism are employed in the context of different problematics and different philosophical assumptions. This article presents ‘relational constructionism’ as a social science perspective.
Dian Marie Hosking   +3 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Constructing the West in Russian Foreign Policy Discourse: Political Actors and Strategies of Representations

open access: yesДискурс Пи, 2017
Drawing on social constructionism, the author reveals discursive mechanisms that are used to construct the West and its relationship with Russia.
T.V. Dubrovskaya
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

The human trafficking debate: Implications for Social Work Practice

open access: yesSocial Work and Society, 2017
The present paper examines the claims making process and the varied constructions of human trafficking as a social problem. We have utilized the theoretical framework of Social Constructionism to answer questions: (1) What is the process utilized in ...
Soma Sen, Yoko Baba
doaj   +2 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Telling stories about story-tellers [PDF]

open access: yesAthenea Digital, 2002
There are people who leave us with a text as their legacy. Their text. Sometimes it is a masterpiece, or a huge amount of work, a fertile and essential one. But there are people who leave us with something more, too: their words, their life. Rex Stainton-
Ibáñez Gracia, Tomás   +1 more
doaj  

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